Elisa Vs. Pcrvirus Detection

Description: Mouse Total IgG Antibody Detection Kit

Description: JBS True Blue

Description: Apoptosis, or programmed cell death, occurs during normal cellular differentiation and development of multicellular organism. It is induced by certain cytokines including TNF and Fas ligand in the TNF family through their death domain containing receptors. TRAIL/Apo2L is a new member of the TNF family which is expressed in a variety of human tissues. Similar to TNF and Fas ligand, TRAIL induces apoptosis and NF-κB activation in many tissues and cells. Its receptors include the death domain containing proteins DR4 and DR5, both of which mediate TRAIL induced cell death. Two decoy receptors, DcR1 and DcR2, have also been identified. Both of these proteins contain an extracellular TRAIL binding domain but lack intracellular signaling domains. Overexpression of either DcR1 or DcR2 attenuates TRAIL-induced apoptosis.;;For images please see PDF data sheet

Description: Members in the TNF superfamily regulate immune responses and induce apoptosis. Two novel members were recently identified by several groups and designated BAFF and APRIL. Both proteins stimulate B cell proliferation, humoral immune responses, NF-κB activation, and apoptosis. Two receptors, TACI and BCMA, recognize both BAFF and APRIL; a third receptor, BAFF-R, is specific for BAFF. These ligands and their receptors are involved in the development of autoimmune diseases as well as cancer.;;For images please see PDF data sheet

Description: A Rabbit polyclonal antibody against Human Versican (VS). This antibody is labeled with APC.

Description: A Rabbit polyclonal antibody against Human Versican (VS). This antibody is labeled with Biotin.

Description: A Rabbit polyclonal antibody against Human Versican (VS). This antibody is labeled with Cy3.

Description: Cell-mediated immune responses are initiated by T lymphocytes that are themselves stimulated by cognate peptides bound to MHC molecules on antigen-presenting cells (APC). T-cell activation is generally self-limited as activated T cells express receptors such as PD-1 (also known as PDCD-1) that mediate inhibitory signals from the APC. PD-1 can bind two different but related ligands, PD-L1 and PD-L2. PD-L1 is a B7-related protein that inhibits cell-mediated immune responses by reducing the secretion of IL-2 and IL-10 from memory T cells. This suggests that PD-L1 may be useful in reducing allogenic CD4+ memory T-cell responses to endothelial cells, thereby reducing the likelihood of host immune responses to allografts.

Description: The 4x Detection Buffer is optimized for use with the PRMT5 Homogeneous Assay Kit (BPS Bioscience #52052).

Description: HMGB1 Detection Kit

Description: The members of the SAP90/PSD-95-associated protein (SAPAP) family (also known as the DLGAP family) specifically interact with PSD-95/SAP90, a membrane-associated guanylate kinase localized at postsynaptic density (PSD) in neuronal cells. The SAPAP proteins are thought to be adaptor proteins that also interact with different synaptic scaffolding proteins, cytoskeletal and signaling components, such as focal adhesion kinase (FAK) and proline-rich tyrosine kinase 2 (PYK2). SAPAP1, -2 and -4 mRNA are targeted to cell bodies, whereas SAPAP3 mRNA is detected mainly in cell bodies. SAPAP1 protein however, is targeted to the synapse and is not reliant on the synaptic localization of PSD-95 or the synaptic scaffolding molecule (S-SCAM). SAPAP3 protein is targeted to dendrites. Recent experiments have suggested that SAPAP3 may be involved in obsessive-compulsive disorder (OCD), as mice lacking SAPAP3 exhibited OCD-like symptoms which could be relieved by lentiviral-mediated selective expression of SAPAP3 in the striatum of SAPAP3-mutant mice. Multiple isoforms of the SAPAP proteins are known to exist.;;For images please see PDF data sheet

Description: TIGIT Antibody: The T cell immunoreceptor with Ig and ITIM domains (TIGIT) is a member of the PVR (poliovirus receptor) family of immunoglobin proteins. It is expressed on several classes of T cells including follicular B helper T cells (TFH). TIGIT has been shown to bind PVR with high affinity; this binding is thought to assist interactions between TFH and dendritic cells to regulate T cell dependent B cell responses (1). Similar to other immune checkpoint proteins such as PD-1, TIGIT is upregulated on exhausted T cells in chronic viral infections and cancer. Blockade of both TIGIT and PD-1 pathways leads to tumor rejection in mice suggesting that it may be of therapeutic use against cancer (2).

Description: The cytokine protein Interleukin-2 is an important factor for the maintenance of_x000D_ CD4+ regulatory T cells. It plays a critical role in the differentiation of CD4+ T cells into a variety of_x000D_ subsets as well as promotes CD8+ T-cell and NK cell cytotoxicity. The Colorimetric Human IL-2_x000D_ Detection Kit is designed for detecting and quantifying human interleukin-2 in cell culture medium._x000D_ Only a few simple steps on a microtiter plate are required for the assay. First, the_x000D_ capture antibody is coated on a 96-well plate. Next, samples containing IL-2 are incubated on the_x000D_ coated plate followed by detecting the captured IL-2 with the detection antibody. Finally, the plate_x000D_ is treated with streptavidin-HRP followed by addition of a colorimetric HRP substrate to produce_x000D_ color, which can then be measured using a UV/Vis spectrophotometer microplate reader.

Description: The cytokine protein Interleukin-2 is an important factor for the maintenance of_x000D_ CD4+ regulatory T cells. It plays a critical role in the differentiation of CD4+ T cells into a variety of_x000D_ subsets as well as promotes CD8+ T-cell and NK cell cytotoxicity. The Colorimetric Human IL-2_x000D_ Detection Kit is designed for detecting and quantifying human interleukin-2 in cell culture medium._x000D_ Only a few simple steps on a microtiter plate are required for the assay. First, the_x000D_ capture antibody is coated on a 96-well plate. Next, samples containing IL-2 are incubated on the_x000D_ coated plate followed by detecting the captured IL-2 with the detection antibody. Finally, the plate_x000D_ is treated with streptavidin-HRP followed by addition of a colorimetric HRP substrate to produce_x000D_ color, which can then be measured using a UV/Vis spectrophotometer microplate reader.

Description: Interleukin-6 is a cytokine produced in response to infections or tissue damage that plays an important role in inflammation, immune response and hematopoiesis. The Colorimetric Human IL-6 Detection Kit is designed for detecting and quantifying human interleukin-6 in cell culture medium. This kit comes in a convenient 96-well format, with capturing and detection antibodies for IL-6, streptavidin-labeled HRP, blocking buffer, IL-6 standard, and colorimetric HRP substrate for a 96-well plate. Only a few simple steps on a microtiter plate are required for the assay. First, the capturing antibody is coated on a 96-well plate. Next, samples containing IL-6 are incubated on the coated plate followed by detecting the captured IL-6 with the detection antibody. Finally, the plate is treated with streptavidin-HRP followed by addition of a colorimetric HRP substrate to produce color, which can then be measured using a UV/Vis spectrophotometer microplate reader.

Description: Liquid Samples

Description: Monkeypox is a viral zoonosis (a virus transmitted to humans from animals) with symptoms very similar to those seen in the past in smallpox patients, although it is clinically less severe. It is caused by the monkeypox virus which belongs to the orthopoxvirus genus of the Poxviridae family. There are two clades of monkeypox virus: the West African clade and the Congo Basin (Central African) clade. The name monkeypox originates from the initial discovery of the virus in monkeys in a Danish laboratory in 1958. The first human case was identified in a child in the Democratic Republic of the Congo in 1970.

Description: Liquid samples and biological fluids

Description: Liquid samples and biological fluids

Description: IFN-γ is a cytokine that is primarily secreted by activated T cells and natural killer (NK) cells and plays an important role in activating innate/adaptive immunity. It also has been recognized as an indicator of T cell activation suggesting IFN-γ activation may be a prerequisite for CAR-T cell activity. The Colorimetric Human IFN-γ Detection Kit is designed for detecting and quantifying human interferon-γ in cell culture medium. Only a few simple steps on a microtiter plate are required for the assay. First, the capture antibody is coated on a 96-well plate. Next, samples containing IFN-γ are incubated on the coated plate followed by detecting the captured IFN-γ with the detection antibody. Finally, the plate is treated with streptavidin-HRP followed by addition of a colorimetric HRP substrate to produce color, which can then be measured using a UV/Vis spectrophotometer microplate reader.

Description: IFN-γ is a cytokine that is primarily secreted by activated T cells and natural killer (NK) cells and plays an important role in activating innate/adaptive immunity. It also has been recognized as an indicator of T cell activation suggesting IFN-γ activation may be a prerequisite for CAR-T cell activity. The Colorimetric Human IFN-γ Detection Kit is designed for detecting and quantifying human interferon-γ in cell culture medium. Only a few simple steps on a microtiter plate are required for the assay. First, the capture antibody is coated on a 96-well plate. Next, samples containing IFN-γ are incubated on the coated plate followed by detecting the captured IFN-γ with the detection antibody. Finally, the plate is treated with streptavidin-HRP followed by addition of a colorimetric HRP substrate to produce color, which can then be measured using a UV/Vis spectrophotometer microplate reader.

Description: Interleukin-10 is a key immunoregulator during various infections that acts as an anti-inflammatory cytokine by inhibiting the activities of Th1, macrophage and NK cells. The IL-10 (Human) Colorimetric ELISA Detection Kit is designed for detecting and quantifying human interleukin-10 in cell culture medium. Only a few simple steps on a microtiter plate are required for the assay. First, the capturing antibody is coated on a 96-well plate. Next, samples containing IL-10 are incubated on the coated plate followed by detecting the captured IL-10 with the detection antibody. Finally, the plate is treated with streptavidin-HRP followed by addition of a colorimetric HRP substrate to produce color, which can then be measured using a UV/Vis spectrophotometer microplate reader.

Description: Interleukin-10 is a key immunoregulator during various infections that acts as an anti-inflammatory cytokine by inhibiting the activities of Th1, macrophage and NK cells. The IL-10 (Human) Colorimetric ELISA Detection Kit is designed for detecting and quantifying human interleukin-10 in cell culture medium. Only a few simple steps on a microtiter plate are required for the assay. First, the capturing antibody is coated on a 96-well plate. Next, samples containing IL-10 are incubated on the coated plate followed by detecting the captured IL-10 with the detection antibody. Finally, the plate is treated with streptavidin-HRP followed by addition of a colorimetric HRP substrate to produce color, which can then be measured using a UV/Vis spectrophotometer microplate reader.