Degradable double hydrophilic block copolymers and tripartite polyionic complex micelles thereof for small interfering ribonucleic acids (siRNA) delivery

Degradable double hydrophilic block copolymers and tripartite polyionic complex micelles thereof for small interfering ribonucleic acids (siRNA) delivery

polymer vectors for gene therapy has been studied as an alternative to viral vectors. In particular, double hydrophilic block copolymers (DHBCs) has shown potential in this domain, but until now research mainly focuses on non-degradable copolymer, which may be restrictions for further development.

To overcome these limitations, we synthesized DHBC (PEG43-b-PCL12 (COOH) 6.5) composed of poly (ethylene glycol) (PEG) non-ionic and bioeliminable block and carboxylic poly acid-functionalized degradable (ε-caprolactone) (PCL) block. DHBC potential as a genuine vector for small interfering ribonucleic acid (siRNA) to formulate tripartite polyionic complex (PIC) micelles with poly (lysine) (PLL) is evaluated.

We first study the impact of the cost ratio (R) on the size and zeta potential of micelles produced. With the cost ratio of R = 1, the formulations with optimized physico-chemical properties demonstrated the ability to complex 75% of the siRNA. We demonstrate the stability of the micelles at pH 7.4 and at pH 5 disturbance, which allows the pH-triggered release of siRNA and proven character of the pH-responsive micelles tripartite stimuli.

In addition, the PIC micelles tripartite non-cytotoxic proven below 40 ug / mL. Potential siRNA vector is then evaluated in vitro: it was found that the tripartite PIC micelles are allowed siRNA internalization into 3 times higher than the PLL polyplexes in murine mesenchymal stem cells, and is able to transfect human breast cancer cells. Overall, these data sets pre-validate the use of degradable DHBC as non-viral vectors for the encapsulation and controlled release of siRNA, which is why it may be a sound alternative for non-degradable and / or cytotoxic polycationic vector.

Degradable double hydrophilic block copolymers and tripartite polyionic complex micelles thereof for small interfering ribonucleic acids (siRNA) delivery
Degradable double hydrophilic block copolymers and tripartite polyionic complex micelles thereof for small interfering ribonucleic acids (siRNA) delivery

Circular role Ribonucleic Acid in the Treatment of Traumatic Brain and Spinal Cord Injury

The causal and pathogenetic factors associated with traumatic brain injury (TBI) and spinal cord injury (SCI) complex. This complexity is a contributory factor in the outcome of a minimal increase of individuals injured. Several studies have demonstrated the potential of stem cells to facilitate neuronal growth and improve results in a variety of neurological conditions, including TBI and SCI. However, the efficiency of the delivery of stem cells at the injured site is open to question.

Circular ribonucleic acid (RNA circular) have recently become the focus of attention because of the different functions and features in vivo. Exosomes have a close relationship with a circular RNA and may have a significant impact on the circular RNA expression.

Here, we review the circular RNA specific functions, exosomes, and stem cells in the central nervous system conditions, mainly TBI and SCI, and trying to show the relationship between them. Our analysis shows a circular RNA’s role in the brain / spinal cord injury for a multifaceted, as they can modulate several signaling mechanisms while also acting as a sponge for microRNAs and bind to their sites. In addition, the circular RNA can activate some biological activity, molecular and cellular in the wake of injury to the brain bone / spine. Thus, both non-pharmacological interventions and pharmacological regulation centered on a circular RNA can promise to TBI and SCI.

Breast Panel Multi-Tumor control slides

TS901 Set of 5
EUR 261.6

Breast Panel Multi-Tumor control slides

TS901-25 Set of 25
EUR 582

Purified Influenza A Neuraminidase (H1N1-NA) protein control for western blot

H1N1NA11-C 100 ul
EUR 343.2

Goat IgG (-ve control for flow cytometry) (isotype control)

20011-100 100 test
EUR 123.6

BSA Control for AGE-BSA

35R-AA007 10 mg
EUR 268.8
Description: BSA Control for AGE protein (BSA modified), Cat No. 30R-AA007

BSA Control for Age-BSA

2221-BSA
EUR 210

Flow Control Fitting for Blowgun

FLY1252 EACH
EUR 53.92

Flow Control Fitting for Flypad

FLY1254 EACH
EUR 67.26

Control for Ckit, 6 samples (1.5mm)

CKIT061 1
EUR 102
Description: Gastrointestinal stroma tumors, 6 cores, 3 cases in duplicates showing strong, moderate and no expression of cKit molecule.

Control for DOG1, 3 cases (1.5mm)

DOG1061 1
EUR 102
Description: IHC control array containing 3 GIST cases of strong, moderate, weak/nil DOG1 expressers in duplicates

Control for ER, 4 cases (1.5mm)

ERC081 1
EUR 102
Description: IHC control array containing 4 breast cancer cases of strong, moderate, weak/nil estrogen receptor (ER) expressers in duplicates

SLLK, Control Peptide for TSP1 Inhibitor

HY-P0301 1mg
EUR 159.6

Control for HER2, 4 cases (1.5mm)

HRC081 1
EUR 102
Description: IHC control array containing 4 breast cancer cases of strong, moderate, low and negative HER2 breast cancer expressers in duplicates

Control for PR, 3 cases (1.5mm)

PRC061 1
EUR 102
Description: IHC control array containing 3 breast cancer cases of strong, moderate, low/negative progesterone receptor (PR) expressers in duplicates

PAS/Glycogen, For Digestion (Control Slides)

TCS0024-100 100 Slides
EUR 847.2

PAS/Glycogen, For Digestion (Control Slides)

TCS0024-25 25 Slides
EUR 278.4

PAS/Glycogen, For Digestion (Control Slides)

TCS0024-5 5 Slides
EUR 117.6

Thiostatin Rat protein, control for western

TSTN11-C 100 ul
EUR 343.2

Control/Blocking peptide for Human WNT5a

WNT511-P 100 ug
EUR 196.8

Negative Control Antibody for Mouse Monoclonals

V8785-100UG 100ug
EUR 499
Description: To serve as a true negative control for various procedures, this monoclonal IgG should be used under the identical conditions and at the same dilution as the rabbit monoclonal antibody being used for a positive reaction.

Negative Control Antibody for Mouse Monoclonals

V8785-20UG 20ug
EUR 219
Description: To serve as a true negative control for various procedures, this monoclonal IgG should be used under the identical conditions and at the same dilution as the rabbit monoclonal antibody being used for a positive reaction.

Negative Control Antibody for Mouse Monoclonals

V8785SAF-100UG 100ug
EUR 499
Description: To serve as a true negative control for various procedures, this monoclonal IgG should be used under the identical conditions and at the same dilution as the rabbit monoclonal antibody being used for a positive reaction.

Deer IgG, semi-pure for ELISA (Control, non-immune, isotype control)

20024-2 100 ug
EUR 270

Holder for Plasmid Midi, Maxi and Maxi plus, Ion Exchange column

FAPDE-holder-for-ion-exchange 1 prep
EUR 189.6

Eppendorf Centrifuge 5430R Knob Control Refrigerated- IVD Only

E5428000465 EACH
EUR 7164.9

Rec. Human CD21 protein control for WB

CD21-C 100 ul
EUR 343.2

Mouse Ceruloplasmin protein control for western blot

CP16-C 100 ul
EUR 343.2

Rat Ceruloplasmin protein control for western blot

CP17-C 100 ul
EUR 343.2

Bovine Adenosine deaminase protein control for Western

ADA11-C 100 ul
EUR 343.2

Purified Flagellin (salmonella) protein control for WB

FLGN17-C 100 ul
EUR 343.2

Mouse IgG (-ve control for flow cytometry)

20008-1-100 100 tests
EUR 123.6

Rabbit IgG (-ve control for flow cytometry)

20009-1-100 100 tests
EUR 123.6

Human Apolipoprotein B protein control for WB

APOB21-C 100 ul
EUR 343.2

Positive Control for Anti-Human CYP1A2 Antibody

P1A2CON 100 uL
EUR 150

Chicken Egg Ovalbumin protein control for Western

OVA11-C 100 ul
EUR 343.2

Positive Control for Anti-Rat CYP2B1 Antibody

P2B1PTCON 100 uL
EUR 150

Positive Control for Anti-Rat CYP2C Antibody

P2CCON 100 uL
EUR 150

Positive Control for Anti-Rat CYP2D Antibody

P2DCON 100 uL
EUR 150

Positive Control for Anti-Human CYP2E1 Antibody

P2E1PTCON 100 uL
EUR 150

Positive Control for Anti-Rat CYP3A2 Antibody

P3A2PTCON 100 uL
EUR 150

Positive Control for Anti-Human CYP3A Antibody

P3ACON 100 uL
EUR 150

Purified bovine Lactoferrin protein control for Western

LTF13-C 100 ul
EUR 343.2

Positive Control for Anti-Rat MEH Antibody

MEHCON 100 uL
EUR 150

Mouse negative control sera (purified) for IHC

NCM802M 7 ml
EUR 238.8

Control/Blocking peptide for Ephrin-B2 antibody

NIVE2B-C 100 ug
EUR 196.8

SLLK, Control Peptide for TSP1 Inhibitor(TFA)

HY-P0301A 5mg
EUR 456

Haptoglobin Human Plasma protein control for WB

HGLB18-C 100 ul
EUR 343.2

Human Hemopexin purified protein control for Western

HPEX11-C 100 ul
EUR 343.2

Hemopexin Mouse, purified protein control for Western

HPEX16-C 100 ul
EUR 343.2

Control Sections for FD NeuroSilver™ Kit

PCS101 each
EUR 69.6

Positive Control for Anti-Human CYP1B1 Antibody

PH1B1CON 100 uL
EUR 150

Purified, Bovine S100 protein control for WB

S1001-C 100 ul
EUR 343.2

Purified, Human S100 protein control for WB

S1002-C 100 ul
EUR 343.2

Control/Blocking peptide for Mouse Vimentin (Vim)

VIM11-C 100 ug
EUR 196.8

Control/Blocking peptide for Human WNT-1

WNT111-P 100 ug
EUR 548.4

Control siRNA Vector (pGB-control)

9500C-20
EUR 405.6

Rabbit Anti-Hemagglutinin Influenza A Virus H1N1 H1 (Pan H1N1 reacts with multiple strains of H1N1) IgG, purified

H1N1-02-A 100 ul
EUR 578.4

Purified human Catalase (CATL) protein control for WB

CATL11-C 100 ul
EUR 343.2

Positive Control for Anti-Human Cytochrome b5 Antibody

Cb5CON 100 uL
EUR 150

Chicken Egg Conalbumin (ovotransferrin) protein control for Western

CECA15-C 100 ul
EUR 343.2

Chicken Egg white proteins total control for Western

CEGW12-C 100 ul
EUR 343.2

Chicken Egg yellow proteins total control for Western

CEYP12-C 100 ul
EUR 343.2

Purified Cholera Toxin protein control for Western Blot

CTOX11-C 100 ul
EUR 343.2

Chicken Ovomucoid (trypsin inhibitor) protein control for Western

COVM13-C 100 ul
EUR 343.2

Rabbit Beta Actin (muscle) protein control for Western

ACTB15-C 100 ul
EUR 388.8

Chicken Serum Albumin protein control for Western blot

ALBC15-C 100 ul
EUR 343.2

Monkey (Rhesus) Serum Albumin protein control for WB

ALBMK21-C 100 ul
EUR 343.2

Monkey (Rhesus) Serum Albumin protein control for WB

ALBMK22-C 100 ul
EUR 343.2

Purified Human Neutrophil Elastase protein control for WB

ESTE11-C 100 ul
EUR 343.2

Human Apolipoprotein C-I protein control for WB

APOC11-C 100 ul
EUR 343.2

Human Apolipoprotein C-II protein control for WB

APOC22-C 100 ul
EUR 343.2

Human Apolipoprotein C-III protein control for WB

APOC32-C 100 ul
EUR 343.2

Human plasma Apolipoprotein E protein control for WB

APOE13-C 100 ul
EUR 343.2

Human Plasma Apolipoprotein J protein control for WB

APOJ13-C 100 ul
EUR 343.2

Recombinant Beta Lactamase protein control for Western blot

BLAC11-C 100 ul
EUR 343.2

Positive Control for Anti-Rat CYP1A1/1A2 Antibody

P1ACON 100 uL
EUR 150

Positive Control for Anti-Rat CHP2B1/2 Antibody

P2B12PTCON 100 uL
EUR 150

Purified Lassa fever Nucleoprotein control for Western Blotting

LFNP15-C-10 100 ul
EUR 343.2

Myoglobin, Human Cardiac, purified protein control for western

MYG17-C 100 ul
EUR 343.2

Purified Nipah virus Glycoprotein control for Western Blotting

NIV11-C 100 ul
EUR 343.2

Purified Nipah virus Nucleoprotein control for Western Blotting

NIV21-C 100 ul
EUR 270

Control/Blocking peptide for Mouse Histone deacetylase 1

HDAC111-P 100 ug
EUR 196.8

Human Prothrombin (Factor II) protein control for Western

PRTN11-C 100 ul
EUR 343.2

Mouse Prothrombin (Factor II) protein control for Western

PRTN13-C 100 ul
EUR 343.2

Human Pancreatic Amylase protein control for Western blot

PAMY13-C 100 ul
EUR 343.2

Control sections for FD NeuroApop™ Kit (frozen)

PCS102- each
EUR 87.6

Control sections for FD NeuroApop™ Kit (paraffin)

PCS102-1 each
EUR 80.44
Description: Best quality products

Control sections for FD NeuroApop™ Kit (frozen)

PCS102-2 each
EUR 80.54
Description: Best quality products

Human Salivary Amylase protein positive control for WB

SAMY16-C 100 ul
EUR 343.2

Purified, recombinant Human TACE control protein for WB

TACE11-C 100 ul
EUR 343.2

Purified Human Survivin protein for WB +ve control

SURV11-C 100 ul
EUR 343.2

Eppendorf Centrifuge 5425R Keypad Control With Rotor Refrigerated EU-IVD

E5406000062 EACH
EUR 5434.38

Eppendorf Centrifuge 5425R Keypad Control Without Rotor Refrigerated EU-IVD

E5406000267 EACH
EUR 5055.9

Eppendorf Centrifuge 5425R Knob Control With Rotor Refrigerated EU-IVD

E5406000461 EACH
EUR 5434.38

Eppendorf Centrifuge 5425R Knob Control Without Rotor Refrigerated EU-IVD

E5406000666 EACH
EUR 5055.9

Quality Control

abx098966-1vial 1 vial
EUR 360

pMD18- Control

PVT10563 2 ug
EUR 319.2

pMD19- Control

PVT10564 2 ug
EUR 319.2

Influenza A virus (H1N1) matrix protein 2 Control/blocking peptide

M2E16-P 100 ug
EUR 196.8

NATtrol Influenza A H1N1 Positive Control (6 X 0.5 mL)

NATFLUAH1N1-6MC 6 X 0.5 mL
EUR 278.4
Description: Please contact Gentaur in order to receive the datasheet of the product.

Rabbit Anti-Hemagglutinin Influenza A Virus H1N1 H1 (H1N1) (A/New Caledonia/20/99) IgG

H1N1-01-A 100 ul
EUR 578.4

Rat neurofascin (Nfasc)-control Control/blocking peptide

AB-23249-CP 100ug
EUR 196.8

Camelpox virus H3L/p35 protein control for western blot

CPOX11-C 100 ul
EUR 343.2

Chicken Egg proteins total (whole egg) control for Western

CEGT11-C 100 ul
EUR 343.2

Chicken Egg white lysozyme (muramidase) protein control for Western

CELY14-C 100 ul
EUR 343.2

Negative Control for Rabbit Monoclonal Antibodies (NCRBM/1520R) Antibody

BNC941520-100 100uL
EUR 238.8
Description: Primary antibody against Negative Control for Rabbit Monoclonal Antibodies (NCRBM/1520R),CF594 conjugate, Concentration: 0.1mg/mL

Negative Control for Rabbit Monoclonal Antibodies (NCRBM/1520R) Antibody

BNC941520-500 500uL
EUR 652.8
Description: Primary antibody against Negative Control for Rabbit Monoclonal Antibodies (NCRBM/1520R),CF594 conjugate, Concentration: 0.1mg/mL

Negative Control for Rabbit Monoclonal Antibodies (NCRBM/1520R) Antibody

BNCA1520-250 250uL
EUR 459.6
Description: Primary antibody against Negative Control for Rabbit Monoclonal Antibodies (NCRBM/1520R),APC conjugate, Concentration: 0.1mg/mL

Human Liver Cathepsin B protein control for Western blot

CTHB11-C 100 ul
EUR 343.2

Human Liver Cathepsin D protein control for Western blot

CTHD11-C 100 ul
EUR 343.2

Human Liver Cathepsin G protein control for Western blot

CTHG11-C 100 ul
EUR 343.2

Human Liver Cathepsin H protein control for Western blot

CTHH11-C 100 ul
EUR 343.2

Human Liver Cathepsin L protein control for Western blot

CTHL11-C 100 ul
EUR 343.2

Negative Control for Rabbit Monoclonal Antibodies (NCRBM/1520R) Antibody

BNC551520-100 100uL
EUR 238.8
Description: Primary antibody against Negative Control for Rabbit Monoclonal Antibodies (NCRBM/1520R),CF555 conjugate, Concentration: 0.1mg/mL

Negative Control for Rabbit Monoclonal Antibodies (NCRBM/1520R) Antibody

BNC551520-500 500uL
EUR 652.8
Description: Primary antibody against Negative Control for Rabbit Monoclonal Antibodies (NCRBM/1520R),CF555 conjugate, Concentration: 0.1mg/mL

Negative Control for Rabbit Monoclonal Antibodies (NCRBM/1520R) Antibody

BNC611520-100 100uL
EUR 238.8
Description: Primary antibody against Negative Control for Rabbit Monoclonal Antibodies (NCRBM/1520R),CF660R conjugate, Concentration: 0.1mg/mL

Negative Control for Rabbit Monoclonal Antibodies (NCRBM/1520R) Antibody

BNC611520-500 500uL
EUR 652.8
Description: Primary antibody against Negative Control for Rabbit Monoclonal Antibodies (NCRBM/1520R),CF660R conjugate, Concentration: 0.1mg/mL

Negative Control for Rabbit Monoclonal Antibodies (NCRBM/1520R) Antibody

BNUM1520-50 50uL
EUR 474
Description: Primary antibody against Negative Control for Rabbit Monoclonal Antibodies (NCRBM/1520R), 1mg/mL

Negative Control for Rabbit Monoclonal Antibodies (NCRBM/1520R) Antibody

BNCP1520-250 250uL
EUR 459.6
Description: Primary antibody against Negative Control for Rabbit Monoclonal Antibodies (NCRBM/1520R),PerCP conjugate, Concentration: 0.1mg/mL

Negative Control for Rabbit Monoclonal Antibodies (NCRBM/1520R) Antibody

BNCR1520-250 250uL
EUR 459.6
Description: Primary antibody against Negative Control for Rabbit Monoclonal Antibodies (NCRBM/1520R),RPE conjugate, Concentration: 0.1mg/mL

Negative Control for Rabbit Monoclonal Antibodies (NCRBM/1520R) Antibody

BNC431520-100 100uL
EUR 238.8
Description: Primary antibody against Negative Control for Rabbit Monoclonal Antibodies (NCRBM/1520R),CF543 conjugate, Concentration: 0.1mg/mL

Negative Control for Rabbit Monoclonal Antibodies (NCRBM/1520R) Antibody

BNC431520-500 500uL
EUR 652.8
Description: Primary antibody against Negative Control for Rabbit Monoclonal Antibodies (NCRBM/1520R),CF543 conjugate, Concentration: 0.1mg/mL

Purified Mouse serum albumin protein control for Western blot

ALB11-C 100 ul
EUR 343.2

Purified Human serum albumin protein control for Western blot

ALBH13-C 100 ul
EUR 343.2

Purified rat serum albumin protein control for Western blot

ALBR12-C 100 ul
EUR 343.2

Purified Sheep serum albumin protein control for Western blot

ALBSH20-C 100 ul
EUR 343.2

Negative Control for Rabbit Monoclonal Antibodies (NCRBM/1520R) Antibody

BNC051520-100 100uL
EUR 238.8
Description: Primary antibody against Negative Control for Rabbit Monoclonal Antibodies (NCRBM/1520R),CF405M conjugate, Concentration: 0.1mg/mL

Negative Control for Rabbit Monoclonal Antibodies (NCRBM/1520R) Antibody

BNC051520-500 500uL
EUR 652.8
Description: Primary antibody against Negative Control for Rabbit Monoclonal Antibodies (NCRBM/1520R),CF405M conjugate, Concentration: 0.1mg/mL

Negative Control for Rabbit Monoclonal Antibodies (NCRBM/1520R) Antibody

BNC401520-100 100uL
EUR 238.8
Description: Primary antibody against Negative Control for Rabbit Monoclonal Antibodies (NCRBM/1520R),CF640R conjugate, Concentration: 0.1mg/mL

Negative Control for Rabbit Monoclonal Antibodies (NCRBM/1520R) Antibody

BNC401520-500 500uL
EUR 652.8
Description: Primary antibody against Negative Control for Rabbit Monoclonal Antibodies (NCRBM/1520R),CF640R conjugate, Concentration: 0.1mg/mL

Negative Control for Rabbit Monoclonal Antibodies (NCRBM/1520R) Antibody

BNC811520-100 100uL
EUR 238.8
Description: Primary antibody against Negative Control for Rabbit Monoclonal Antibodies (NCRBM/1520R),CF680R conjugate, Concentration: 0.1mg/mL

Negative Control for Rabbit Monoclonal Antibodies (NCRBM/1520R) Antibody

BNC811520-500 500uL
EUR 652.8
Description: Primary antibody against Negative Control for Rabbit Monoclonal Antibodies (NCRBM/1520R),CF680R conjugate, Concentration: 0.1mg/mL

Negative Control for Rabbit Monoclonal Antibodies (NCRBM/1520R) Antibody

BNC801520-100 100uL
EUR 238.8
Description: Primary antibody against Negative Control for Rabbit Monoclonal Antibodies (NCRBM/1520R),CF680 conjugate, Concentration: 0.1mg/mL

Negative Control for Rabbit Monoclonal Antibodies (NCRBM/1520R) Antibody

BNC801520-500 500uL
EUR 652.8
Description: Primary antibody against Negative Control for Rabbit Monoclonal Antibodies (NCRBM/1520R),CF680 conjugate, Concentration: 0.1mg/mL

Negative Control for Rabbit Monoclonal Antibodies (NCRBM/1520R) Antibody

BNCH1520-100 100uL
EUR 238.8
Description: Primary antibody against Negative Control for Rabbit Monoclonal Antibodies (NCRBM/1520R),Horseradish Peroxidase conjugate, Concentration: 0.1mg/mL

Negative Control for Rabbit Monoclonal Antibodies (NCRBM/1520R) Antibody

BNCH1520-500 500uL
EUR 652.8
Description: Primary antibody against Negative Control for Rabbit Monoclonal Antibodies (NCRBM/1520R),Horseradish Peroxidase conjugate, Concentration: 0.1mg/mL

Negative Control for Rabbit Monoclonal Antibodies (NCRBM/1520R) Antibody

BNC041520-100 100uL
EUR 238.8
Description: Primary antibody against Negative Control for Rabbit Monoclonal Antibodies (NCRBM/1520R),CF405S conjugate, Concentration: 0.1mg/mL

Negative Control for Rabbit Monoclonal Antibodies (NCRBM/1520R) Antibody

BNC041520-500 500uL
EUR 652.8
Description: Primary antibody against Negative Control for Rabbit Monoclonal Antibodies (NCRBM/1520R),CF405S conjugate, Concentration: 0.1mg/mL

Negative Control for Rabbit Monoclonal Antibodies (NCRBM/1520R) Antibody

BNC681520-100 100uL
EUR 238.8
Description: Primary antibody against Negative Control for Rabbit Monoclonal Antibodies (NCRBM/1520R),CF568 conjugate, Concentration: 0.1mg/mL

Negative Control for Rabbit Monoclonal Antibodies (NCRBM/1520R) Antibody

BNC681520-500 500uL
EUR 652.8
Description: Primary antibody against Negative Control for Rabbit Monoclonal Antibodies (NCRBM/1520R),CF568 conjugate, Concentration: 0.1mg/mL

Negative Control for Rabbit Monoclonal Antibodies (NCRBM/1520R) Antibody

BNC701520-100 100uL
EUR 238.8
Description: Primary antibody against Negative Control for Rabbit Monoclonal Antibodies (NCRBM/1520R),CF770 conjugate, Concentration: 0.1mg/mL

Negative Control for Rabbit Monoclonal Antibodies (NCRBM/1520R) Antibody

BNC701520-500 500uL
EUR 652.8
Description: Primary antibody against Negative Control for Rabbit Monoclonal Antibodies (NCRBM/1520R),CF770 conjugate, Concentration: 0.1mg/mL

Negative Control for Rabbit Monoclonal Antibodies (NCRBM/1520R) Antibody

BNCAP1520-100 100uL
EUR 238.8
Description: Primary antibody against Negative Control for Rabbit Monoclonal Antibodies (NCRBM/1520R),Alkaline Phosphatase conjugate, Concentration: 0.1mg/mL

Negative Control for Rabbit Monoclonal Antibodies (NCRBM/1520R) Antibody

BNCAP1520-500 500uL
EUR 652.8
Description: Primary antibody against Negative Control for Rabbit Monoclonal Antibodies (NCRBM/1520R),Alkaline Phosphatase conjugate, Concentration: 0.1mg/mL

Negative Control for Rabbit Monoclonal Antibodies (NCRBM/1520R) Antibody

BNC881520-100 100uL
EUR 238.8
Description: Primary antibody against Negative Control for Rabbit Monoclonal Antibodies (NCRBM/1520R),CF488A conjugate, Concentration: 0.1mg/mL

Negative Control for Rabbit Monoclonal Antibodies (NCRBM/1520R) Antibody

BNC881520-500 500uL
EUR 652.8
Description: Primary antibody against Negative Control for Rabbit Monoclonal Antibodies (NCRBM/1520R),CF488A conjugate, Concentration: 0.1mg/mL

Negative Control for Rabbit Monoclonal Antibodies (NCRBM/1520R) Antibody

BNCB1520-100 100uL
EUR 238.8
Description: Primary antibody against Negative Control for Rabbit Monoclonal Antibodies (NCRBM/1520R),Biotin conjugate, Concentration: 0.1mg/mL

Negative Control for Rabbit Monoclonal Antibodies (NCRBM/1520R) Antibody

BNCB1520-500 500uL
EUR 652.8
Description: Primary antibody against Negative Control for Rabbit Monoclonal Antibodies (NCRBM/1520R),Biotin conjugate, Concentration: 0.1mg/mL

Negative Control for Rabbit Monoclonal Antibodies (NCRBM/1520R) Antibody

BNC471520-100 100uL
EUR 238.8
Description: Primary antibody against Negative Control for Rabbit Monoclonal Antibodies (NCRBM/1520R),CF647 conjugate, Concentration: 0.1mg/mL

Negative Control for Rabbit Monoclonal Antibodies (NCRBM/1520R) Antibody

BNC471520-500 500uL
EUR 652.8
Description: Primary antibody against Negative Control for Rabbit Monoclonal Antibodies (NCRBM/1520R),CF647 conjugate, Concentration: 0.1mg/mL

Negative Control for Rabbit Monoclonal Antibodies (NCRBM/1520R) Antibody

BNUB1520-100 100uL
EUR 250.8
Description: Primary antibody against Negative Control for Rabbit Monoclonal Antibodies (NCRBM/1520R), Concentration: 0.2mg/mL

Negative Control for Rabbit Monoclonal Antibodies (NCRBM/1520R) Antibody

BNUB1520-500 500uL
EUR 549.6
Description: Primary antibody against Negative Control for Rabbit Monoclonal Antibodies (NCRBM/1520R), Concentration: 0.2mg/mL

Purified Human C-Reactive Protein (CRP) control for WB

CRP12-C 100 ul
EUR 343.2

Purified Rat C-Reactive Protein (CRP) control for WB

CRP16-C 100 ul
EUR 343.2

Purified Dog C-Reactive Protein (CRP) control for WB

CRP18-C 100 ul
EUR 343.2

Recombinant (CHO) human DNAse I Protein control for WB

DNASE12-C 100 ul
EUR 343.2

Alpha 2-Macroglobulin (A2M), Human protein control for WB

A2MG11-C 100 ul
EUR 343.2

Alpha-1-Acid Glycoprotein Protein, Dog, control for western

A1AG17-C 100 ul
EUR 343.2

Alpha-1-Acid Glycoprotein Protein, Mouse, control for western

A1AG18-C 100 ul
EUR 343.2

Alpha 1-Antitrypsin (A1AT), Human protein control for WB

A1AT11-C 100 ul
EUR 343.2

Mouse Angiopoietin 3 (Ang-3) protein control for WB

ANG31-C 100 ul
EUR 343.2


Disease coronavirus (COVID-19), which is caused by a coronavirus 2 acute respiratory syndrome (SARS-CoV-2), has been declared a pandemic. We here report the four COVID-19 cases with long-term positive viral ribonucleic acid (RNA) for about 61 days. Although treatment with human recombinant interferon, plasma recovered from COVID-19 patients, Arbidol, etc., the results of nucleic acid is still positive for SARS-CoV-2. After treatment with ritonavir danoprevir (DNVr, 100/100 mg, once daily), four patients showed 2-3 consecutive negative SARS-CoV-2 RNA and thus out of the hospital.

Kathleen

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HIF-1 modulates dietary restriction-mediated lifespan extension via IRE-1 in Caenorhabditis elegans.

HIF-1 modulates dietary restriction-mediated lifespan extension via IRE-1 in Caenorhabditis elegans.

Expression of Staphylococcus aureus clumping factor A in Lactococcus lactis subsp. cremoris using a new shuttle vector.

Expression of Staphylococcus aureus clumping factor A in Lactococcus lactis subsp. cremoris using a new shuttle vector.

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