Degradable double hydrophilic block copolymers and tripartite polyionic complex micelles thereof for small interfering ribonucleic acids (siRNA) delivery

Degradable double hydrophilic block copolymers and tripartite polyionic complex micelles thereof for small interfering ribonucleic acids (siRNA) delivery

polymer vectors for gene therapy has been studied as an alternative to viral vectors. In particular, double hydrophilic block copolymers (DHBCs) has shown potential in this domain, but until now research mainly focuses on non-degradable copolymer, which may be restrictions for further development.

To overcome these limitations, we synthesized DHBC (PEG43-b-PCL12 (COOH) 6.5) composed of poly (ethylene glycol) (PEG) non-ionic and bioeliminable block and carboxylic poly acid-functionalized degradable (ε-caprolactone) (PCL) block. DHBC potential as a genuine vector for small interfering ribonucleic acid (siRNA) to formulate tripartite polyionic complex (PIC) micelles with poly (lysine) (PLL) is evaluated.

We first study the impact of the cost ratio (R) on the size and zeta potential of micelles produced. With the cost ratio of R = 1, the formulations with optimized physico-chemical properties demonstrated the ability to complex 75% of the siRNA. We demonstrate the stability of the micelles at pH 7.4 and at pH 5 disturbance, which allows the pH-triggered release of siRNA and proven character of the pH-responsive micelles tripartite stimuli.

In addition, the PIC micelles tripartite non-cytotoxic proven below 40 ug / mL. Potential siRNA vector is then evaluated in vitro: it was found that the tripartite PIC micelles are allowed siRNA internalization into 3 times higher than the PLL polyplexes in murine mesenchymal stem cells, and is able to transfect human breast cancer cells. Overall, these data sets pre-validate the use of degradable DHBC as non-viral vectors for the encapsulation and controlled release of siRNA, which is why it may be a sound alternative for non-degradable and / or cytotoxic polycationic vector.

Degradable double hydrophilic block copolymers and tripartite polyionic complex micelles thereof for small interfering ribonucleic acids (siRNA) delivery
Degradable double hydrophilic block copolymers and tripartite polyionic complex micelles thereof for small interfering ribonucleic acids (siRNA) delivery

Circular role Ribonucleic Acid in the Treatment of Traumatic Brain and Spinal Cord Injury

The causal and pathogenetic factors associated with traumatic brain injury (TBI) and spinal cord injury (SCI) complex. This complexity is a contributory factor in the outcome of a minimal increase of individuals injured. Several studies have demonstrated the potential of stem cells to facilitate neuronal growth and improve results in a variety of neurological conditions, including TBI and SCI. However, the efficiency of the delivery of stem cells at the injured site is open to question.

Circular ribonucleic acid (RNA circular) have recently become the focus of attention because of the different functions and features in vivo. Exosomes have a close relationship with a circular RNA and may have a significant impact on the circular RNA expression.

Here, we review the circular RNA specific functions, exosomes, and stem cells in the central nervous system conditions, mainly TBI and SCI, and trying to show the relationship between them. Our analysis shows a circular RNA’s role in the brain / spinal cord injury for a multifaceted, as they can modulate several signaling mechanisms while also acting as a sponge for microRNAs and bind to their sites. In addition, the circular RNA can activate some biological activity, molecular and cellular in the wake of injury to the brain bone / spine. Thus, both non-pharmacological interventions and pharmacological regulation centered on a circular RNA can promise to TBI and SCI.

NATtrol Influenza A H1N1, External Run Control, Medium (6 X 1 mL)

NATFLUAH1N1-ERCM 6 X 1 mL
EUR 438

Influenza A virus (H1N1) matrix protein 2 Control/blocking peptide

M2E16-P 100 ug
EUR 196.8

Influenza A H1N1 Nucleoprotein/NP Insect Cell Lysate (WB positive control)

MBS8114643-03mg 0.3mg
EUR 280

Influenza A H1N1 Nucleoprotein/NP Insect Cell Lysate (WB positive control)

MBS8114643-5x03mg 5x0.3mg
EUR 1205

Influenza A H1N1 (A/Fort Monmouth/1/1947) Hemagglutinin/HA Insect Cell Lysate (WB positive control)

MBS8116115-03mg 0.3mg
EUR 280

Influenza A H1N1 (A/Fort Monmouth/1/1947) Hemagglutinin/HA Insect Cell Lysate (WB positive control)

MBS8116115-5x03mg 5x0.3mg
EUR 1205

Influenza A H1N1 (A/Fort Monmouth/1/1947) Hemagglutinin/HA1 HEK293 Cell Lysate (WB positive control)

MBS8116116-03mg 0.3mg
EUR 280

Influenza A H1N1 (A/Fort Monmouth/1/1947) Hemagglutinin/HA1 HEK293 Cell Lysate (WB positive control)

MBS8116116-5x03mg 5x0.3mg
EUR 1205

Influenza A H1N1 (A/WSN/1933) Hemagglutinin/HA Insect Cell Lysate (WB positive control)

MBS8114675-03mg 0.3mg
EUR 280

Influenza A H1N1 (A/WSN/1933) Hemagglutinin/HA Insect Cell Lysate (WB positive control)

MBS8114675-5x03mg 5x0.3mg
EUR 1205

Influenza A H1N1 (A/WSN/33) Hemagglutinin/HA HEK293 Cell Lysate (WB positive control)

MBS8114677-03mg 0.3mg
EUR 280

Influenza A H1N1 (A/WSN/33) Hemagglutinin/HA HEK293 Cell Lysate (WB positive control)

MBS8114677-5x03mg 5x0.3mg
EUR 1205

Influenza A H1N1 (A/Bel/1942) Hemagglutinin/HA1 HEK293 Cell Lysate (WB positive control)

MBS8116114-03mg 0.3mg
EUR 280

Influenza A H1N1 (A/Bel/1942) Hemagglutinin/HA1 HEK293 Cell Lysate (WB positive control)

MBS8116114-5x03mg 5x0.3mg
EUR 1205

Influenza A H1N1 (A/WSN/1933) Hemagglutinin/HA HEK293 Cell Lysate (WB positive control)

MBS8116240-03mg 0.3mg
EUR 280

Influenza A H1N1 (A/WSN/1933) Hemagglutinin/HA HEK293 Cell Lysate (WB positive control)

MBS8116240-5x03mg 5x0.3mg
EUR 1205

Recombinant Purified Hemagglutinin Influenza A Virus (H11N2; A/duck/Yangzhou/906/2002) protein control for Western

H11N2-01-C 100 ul
EUR 343.2

Influenza A H1N1 (A/Denver/1957) Hemagglutinin/HA HEK293 Cell Lysate (WB positive control)

MBS8116188-03mg 0.3mg
EUR 280

Influenza A H1N1 (A/Denver/1957) Hemagglutinin/HA HEK293 Cell Lysate (WB positive control)

MBS8116188-5x03mg 5x0.3mg
EUR 1205

Influenza A H1N1 (A/Ohio/07/2009) Hemagglutinin/HA HEK293 Cell Lysate (WB positive control)

MBS8115761-03mg 0.3mg
EUR 280

Influenza A H1N1 (A/Ohio/07/2009) Hemagglutinin/HA HEK293 Cell Lysate (WB positive control)

MBS8115761-5x03mg 5x0.3mg
EUR 1205

Influenza A H1N1 (A/USSR/90/77) Hemagglutinin/HA Insect Cell Lysate (WB positive control)

MBS8115879-03mg 0.3mg
EUR 280

Influenza A H1N1 (A/USSR/90/77) Hemagglutinin/HA Insect Cell Lysate (WB positive control)

MBS8115879-5x03mg 5x0.3mg
EUR 1205

Influenza A H1N1 (A/USSR/90/77) Neuraminidase/NA HEK293 Cell Lysate (WB positive control)

MBS8115960-03mg 0.3mg
EUR 280

Influenza A H1N1 (A/USSR/90/77) Neuraminidase/NA HEK293 Cell Lysate (WB positive control)

MBS8115960-5x03mg 5x0.3mg
EUR 1205

Influenza A H1N1 (A/USSR/90/1977) Hemagglutinin/HA HEK293 Cell Lysate (WB positive control)

MBS8116241-03mg 0.3mg
EUR 280

Influenza A H1N1 (A/USSR/90/1977) Hemagglutinin/HA HEK293 Cell Lysate (WB positive control)

MBS8116241-5x03mg 5x0.3mg
EUR 1205

Influenza A H1N1 (A/Hawaii/70/2019) Nucleoprotein/NP Insect Cell Lysate (WB positive control)

MBS8119747-03mg 0.3mg
EUR 280

Influenza A H1N1 (A/Hawaii/70/2019) Nucleoprotein/NP Insect Cell Lysate (WB positive control)

MBS8119747-5x03mg 5x0.3mg
EUR 1205

Influenza A H1N1 (A/Texas/05/2009) Hemagglutinin/HA HEK293 Cell Lysate (WB positive control)

MBS8115759-03mg 0.3mg
EUR 280

Influenza A H1N1 (A/Texas/05/2009) Hemagglutinin/HA HEK293 Cell Lysate (WB positive control)

MBS8115759-5x03mg 5x0.3mg
EUR 1205

Influenza A H1N1 (A/Taiwan/01/1986) Hemagglutinin/HA Insect Cell Lysate (WB positive control)

MBS8115874-03mg 0.3mg
EUR 280

Influenza A H1N1 (A/Taiwan/01/1986) Hemagglutinin/HA Insect Cell Lysate (WB positive control)

MBS8115874-5x03mg 5x0.3mg
EUR 1205

Influenza A H1N1 (A/Texas/36/1991) Hemagglutinin/HA Insect Cell Lysate (WB positive control)

MBS8115875-03mg 0.3mg
EUR 280

Influenza A H1N1 (A/Texas/36/1991) Hemagglutinin/HA Insect Cell Lysate (WB positive control)

MBS8115875-5x03mg 5x0.3mg
EUR 1205

Influenza A H1N1 (A/Bel/1942) Hemagglutinin/HA Insect Cells Cell Lysate (WB positive control)

MBS8116113-03mg 0.3mg
EUR 280

Influenza A H1N1 (A/Bel/1942) Hemagglutinin/HA Insect Cells Cell Lysate (WB positive control)

MBS8116113-5x03mg 5x0.3mg
EUR 1205

Influenza A H1N1 (A/New.York/1/1918) Hemagglutinin/HA HEK293 Cell Lysate (WB positive control)

MBS8116183-03mg 0.3mg
EUR 280

Influenza A H1N1 (A/New.York/1/1918) Hemagglutinin/HA HEK293 Cell Lysate (WB positive control)

MBS8116183-5x03mg 5x0.3mg
EUR 1205

Influenza A H1N1 (A/AA/Huston/1945) Hemagglutinin/HA HEK293 Cell Lysate (WB positive control)

MBS8116186-03mg 0.3mg
EUR 280

Influenza A H1N1 (A/AA/Huston/1945) Hemagglutinin/HA HEK293 Cell Lysate (WB positive control)

MBS8116186-5x03mg 5x0.3mg
EUR 1205

Influenza A H1N1 (A/Taiwan/4845/1999) Hemagglutinin/HA HEK293 Cell Lysate (WB positive control)

MBS8116192-03mg 0.3mg
EUR 280

Influenza A H1N1 (A/Taiwan/4845/1999) Hemagglutinin/HA HEK293 Cell Lysate (WB positive control)

MBS8116192-5x03mg 5x0.3mg
EUR 1205

Influenza A H1N1 (A/Pavia/65/2016) Hemagglutinin/HA HEK293 Cell Lysate (WB positive control)

MBS8116212-03mg 0.3mg
EUR 280

Influenza A H1N1 (A/Pavia/65/2016) Hemagglutinin/HA HEK293 Cell Lysate (WB positive control)

MBS8116212-5x03mg 5x0.3mg
EUR 1205

Influenza A H1N1 (A/Tawain/01/1986) Hemagglutinin/HA HEK293 Cell Lysate (WB positive control)

MBS8116242-03mg 0.3mg
EUR 280

Influenza A H1N1 (A/Tawain/01/1986) Hemagglutinin/HA HEK293 Cell Lysate (WB positive control)

MBS8116242-5x03mg 5x0.3mg
EUR 1205

Influenza A H1N1 (A/Texas/36/1991) Hemagglutinin/HA HEK293 Cell Lysate (WB positive control)

MBS8116243-03mg 0.3mg
EUR 280

Influenza A H1N1 (A/Texas/36/1991) Hemagglutinin/HA HEK293 Cell Lysate (WB positive control)

MBS8116243-5x03mg 5x0.3mg
EUR 1205

Influenza A H5N1 Hemagglutinin, (IN) Control Peptide

MBS659985-005mg 0.05mg
EUR 790

Influenza A H5N1 Hemagglutinin, (IN) Control Peptide

MBS659985-5x005mg 5x0.05mg
EUR 3395

Influenza A H1N1 (A/Brisbane/02/2018) Neuraminidase/NA Insect Cell Lysate (WB positive control)

MBS8119887-INQUIRE INQUIRE Ask for price

Influenza A H1N1 (A/Brisbane/02/2018) Nucleoprotein/NP Insect Cell Lysate (WB positive control)

MBS8119889-INQUIRE INQUIRE Ask for price

Influenza A H1N1 (A/Michigan/45/2015) Nucleoprotein/NP Insect Cell Lysate (WB positive control)

MBS8119890-INQUIRE INQUIRE Ask for price

Influenza A H1N1 (A/Brisbane/59/2007) Hemagglutinin/HA HEK293 Cell Lysate (WB positive control)

MBS8114342-03mg 0.3mg
EUR 280

Influenza A H1N1 (A/Brisbane/59/2007) Hemagglutinin/HA HEK293 Cell Lysate (WB positive control)

MBS8114342-5x03mg 5x0.3mg
EUR 1205

Influenza A H1N1 (A/England/195/2009) Hemagglutinin/HA Insect Cell Lysate (WB positive control)

MBS8115755-03mg 0.3mg
EUR 280

Influenza A H1N1 (A/England/195/2009) Hemagglutinin/HA Insect Cell Lysate (WB positive control)

MBS8115755-5x03mg 5x0.3mg
EUR 1205

Influenza A H1N1 (A/England/195/2009) Hemagglutinin/HA HEK293 Cell Lysate (WB positive control)

MBS8115757-03mg 0.3mg
EUR 280

Influenza A H1N1 (A/England/195/2009) Hemagglutinin/HA HEK293 Cell Lysate (WB positive control)

MBS8115757-5x03mg 5x0.3mg
EUR 1205

Influenza A H1N1 (A/Beijing/22808/2009) Hemagglutinin/HA HEK293 Cell Lysate (WB positive control)

MBS8115800-03mg 0.3mg
EUR 280

Influenza A H1N1 (A/Beijing/22808/2009) Hemagglutinin/HA HEK293 Cell Lysate (WB positive control)

MBS8115800-5x03mg 5x0.3mg
EUR 1205

Influenza A H1N1 (A/Beijing/262/1995) Hemagglutinin/HA Insect Cell Lysate (WB positive control)

MBS8115877-03mg 0.3mg
EUR 280

Influenza A H1N1 (A/Beijing/262/1995) Hemagglutinin/HA Insect Cell Lysate (WB positive control)

MBS8115877-5x03mg 5x0.3mg
EUR 1205

Influenza A H1N1 (A/Beijing/262/1995) Hemagglutinin/HA1 HEK293 Cell Lysate (WB positive control)

MBS8115878-03mg 0.3mg
EUR 280

Influenza A H1N1 (A/Beijing/262/1995) Hemagglutinin/HA1 HEK293 Cell Lysate (WB positive control)

MBS8115878-5x03mg 5x0.3mg
EUR 1205

Influenza A H1N1 (A/Albany/12/1951) Hemagglutinin/HA1 HEK293 Cell Lysate (WB positive control)

MBS8116068-03mg 0.3mg
EUR 280

Influenza A H1N1 (A/Albany/12/1951) Hemagglutinin/HA1 HEK293 Cell Lysate (WB positive control)

MBS8116068-5x03mg 5x0.3mg
EUR 1205

Influenza A H1N1 (A/Hawaii/19/2007) Hemagglutinin/HA1 HEK293 Cell Lysate (WB positive control)

MBS8116117-03mg 0.3mg
EUR 280

Influenza A H1N1 (A/Hawaii/19/2007) Hemagglutinin/HA1 HEK293 Cell Lysate (WB positive control)

MBS8116117-5x03mg 5x0.3mg
EUR 1205

Influenza A H1N1 (A/Memphis/1/1987) Hemagglutinin/HA Insect Cell Lysate (WB positive control)

MBS8116118-03mg 0.3mg
EUR 280

Influenza A H1N1 (A/Memphis/1/1987) Hemagglutinin/HA Insect Cell Lysate (WB positive control)

MBS8116118-5x03mg 5x0.3mg
EUR 1205

Influenza A H1N1 (A/Memphis/1/1987) Hemagglutinin/HA1 HEK293 Cell Lysate (WB positive control)

MBS8116119-03mg 0.3mg
EUR 280

Influenza A H1N1 (A/Memphis/1/1987) Hemagglutinin/HA1 HEK293 Cell Lysate (WB positive control)

MBS8116119-5x03mg 5x0.3mg
EUR 1205

Influenza A H1N1 (A/Michigan/45/2015) Hemagglutinin/HA HEK293 Cell Lysate (WB positive control)

MBS8116155-03mg 0.3mg
EUR 280

Influenza A H1N1 (A/Michigan/45/2015) Hemagglutinin/HA HEK293 Cell Lysate (WB positive control)

MBS8116155-5x03mg 5x0.3mg
EUR 1205

Influenza A H1N1 (A/New.Jersey/8/1976) Hemagglutinin/HA HEK293 Cell Lysate (WB positive control)

MBS8116189-03mg 0.3mg
EUR 280

Influenza A H1N1 (A/New.Jersey/8/1976) Hemagglutinin/HA HEK293 Cell Lysate (WB positive control)

MBS8116189-5x03mg 5x0.3mg
EUR 1205

Influenza A H1N1 (A/Iowa/CEID23/2005) Hemagglutinin/HA HEK293 Cell Lysate (WB positive control)

MBS8116197-03mg 0.3mg
EUR 280

Influenza A H1N1 (A/Iowa/CEID23/2005) Hemagglutinin/HA HEK293 Cell Lysate (WB positive control)

MBS8116197-5x03mg 5x0.3mg
EUR 1205

Influenza A H1N1 (A/Thailand/271/2005) Hemagglutinin/HA HEK293 Cell Lysate (WB positive control)

MBS8116198-03mg 0.3mg
EUR 280

Influenza A H1N1 (A/Thailand/271/2005) Hemagglutinin/HA HEK293 Cell Lysate (WB positive control)

MBS8116198-5x03mg 5x0.3mg
EUR 1205

Influenza A H1N1 (A/Florida/04/2017) Hemagglutinin/HA HEK293 Cell Lysate (WB positive control)

MBS8116213-03mg 0.3mg
EUR 280

Influenza A H1N1 (A/Florida/04/2017) Hemagglutinin/HA HEK293 Cell Lysate (WB positive control)

MBS8116213-5x03mg 5x0.3mg
EUR 1205

Influenza A H1N1 (A/Beijing/262/1995) Hemagglutinin/HA HEK293 Cell Lysate (WB positive control)

MBS8116244-03mg 0.3mg
EUR 280

Influenza A H1N1 (A/Beijing/262/1995) Hemagglutinin/HA HEK293 Cell Lysate (WB positive control)

MBS8116244-5x03mg 5x0.3mg
EUR 1205

Influenza A H1N1 (A/New York/18/2009) Hemagglutinin/HA Insect Cell Lysate (WB positive control)

MBS8115765-03mg 0.3mg
EUR 280

Influenza A H1N1 (A/New York/18/2009) Hemagglutinin/HA Insect Cell Lysate (WB positive control)

MBS8115765-5x03mg 5x0.3mg
EUR 1205

Influenza A H1N1 (A/New York/18/2009) Hemagglutinin/HA HEK293 Cell Lysate (WB positive control)

MBS8115767-03mg 0.3mg
EUR 280

Influenza A H1N1 (A/New York/18/2009) Hemagglutinin/HA HEK293 Cell Lysate (WB positive control)

MBS8115767-5x03mg 5x0.3mg
EUR 1205

Influenza A H1N1 (A/New York/1/1918) Hemagglutinin/HA Insect Cell Lysate (WB positive control)

MBS8115829-03mg 0.3mg
EUR 280

Influenza A H1N1 (A/New York/1/1918) Hemagglutinin/HA Insect Cell Lysate (WB positive control)

MBS8115829-5x03mg 5x0.3mg
EUR 1205

Influenza A H1N1 (A/swine/OMS/2112/1995) Hemagglutinin/HA HEK293 Cell Lysate (WB positive control)

MBS8116190-03mg 0.3mg
EUR 280

Influenza A H1N1 (A/swine/OMS/2112/1995) Hemagglutinin/HA HEK293 Cell Lysate (WB positive control)

MBS8116190-5x03mg 5x0.3mg
EUR 1205

Influenza A H1N1 (A/California/04/2009) Hemagglutinin/HA Insect Cell Lysate (WB positive control)

MBS8114350-03mg 0.3mg
EUR 280

Influenza A H1N1 (A/California/04/2009) Hemagglutinin/HA Insect Cell Lysate (WB positive control)

MBS8114350-5x03mg 5x0.3mg
EUR 1205

Influenza A H1N1 (A/California/04/2009) Hemagglutinin/HA HEK293 Cell Lysate (WB positive control)

MBS8114351-03mg 0.3mg
EUR 280

Influenza A H1N1 (A/California/04/2009) Hemagglutinin/HA HEK293 Cell Lysate (WB positive control)

MBS8114351-5x03mg 5x0.3mg
EUR 1205

Influenza A H1N1 (A/California/04/2009) Hemagglutinin/HA HEK293 Cell Lysate (WB positive control)

MBS8114353-03mg 0.3mg
EUR 280

Influenza A H1N1 (A/California/04/2009) Hemagglutinin/HA HEK293 Cell Lysate (WB positive control)

MBS8114353-5x03mg 5x0.3mg
EUR 1205

Influenza A H1N1 (A/California/04/2009) Neuraminidase/NA HEK293 Cell Lysate (WB positive control)

MBS8114360-03mg 0.3mg
EUR 280

Influenza A H1N1 (A/California/04/2009) Neuraminidase/NA HEK293 Cell Lysate (WB positive control)

MBS8114360-5x03mg 5x0.3mg
EUR 1205

Influenza A H1N1 (A/California/04/2009) Neuraminidase/NA Insect Cell Lysate (WB positive control)

MBS8114361-03mg 0.3mg
EUR 280

Influenza A H1N1 (A/California/04/2009) Neuraminidase/NA Insect Cell Lysate (WB positive control)

MBS8114361-5x03mg 5x0.3mg
EUR 1205

Influenza A H1N1 (A/California/07/2009) Hemagglutinin/HA Insect Cell Lysate (WB positive control)

MBS8114410-03mg 0.3mg
EUR 280

Influenza A H1N1 (A/California/07/2009) Hemagglutinin/HA Insect Cell Lysate (WB positive control)

MBS8114410-5x03mg 5x0.3mg
EUR 1205

Influenza A H1N1 (A/California/07/2009) Hemagglutinin/HA HEK293 Cell Lysate (WB positive control)

MBS8114411-03mg 0.3mg
EUR 280

Influenza A H1N1 (A/California/07/2009) Hemagglutinin/HA HEK293 Cell Lysate (WB positive control)

MBS8114411-5x03mg 5x0.3mg
EUR 1205

Influenza A H1N1 (A/WSN/33) Hemagglutinin (HA1 Subunit) HEK293 Cell Lysate (WB positive control)

MBS8114676-03mg 0.3mg
EUR 280

Influenza A H1N1 (A/WSN/33) Hemagglutinin (HA1 Subunit) HEK293 Cell Lysate (WB positive control)

MBS8114676-5x03mg 5x0.3mg
EUR 1205

Influenza A H1N1 (A/California/07/2009) Nucleoprotein/NP Insect Cell Lysate (WB positive control)

MBS8115963-03mg 0.3mg
EUR 280

Influenza A H1N1 (A/California/07/2009) Nucleoprotein/NP Insect Cell Lysate (WB positive control)

MBS8115963-5x03mg 5x0.3mg
EUR 1205

Influenza A H1N1 (A/California/06/2009) Hemagglutinin/HA Insect Cell Lysate (WB positive control)

MBS8115990-03mg 0.3mg
EUR 280

Influenza A H1N1 (A/California/06/2009) Hemagglutinin/HA Insect Cell Lysate (WB positive control)

MBS8115990-5x03mg 5x0.3mg
EUR 1205

Influenza A H1N1 (A/NewJersey/8/1976) Hemagglutinin/HA Insect Cell Lysate (WB positive control)

MBS8116024-03mg 0.3mg
EUR 280

Influenza A H1N1 (A/NewJersey/8/1976) Hemagglutinin/HA Insect Cell Lysate (WB positive control)

MBS8116024-5x03mg 5x0.3mg
EUR 1205

Influenza A H1N1 (A/NewJersey/8/1976) Hemagglutinin/HA1 HEK293 Cell Lysate (WB positive control)

MBS8116025-03mg 0.3mg
EUR 280

Influenza A H1N1 (A/NewJersey/8/1976) Hemagglutinin/HA1 HEK293 Cell Lysate (WB positive control)

MBS8116025-5x03mg 5x0.3mg
EUR 1205

Influenza A H1N1 (A/Michigan/45/2015) Hemagglutinin/HA1 HEK293 Cell Lysate (WB positive control)

MBS8116154-03mg 0.3mg
EUR 280

Influenza A H1N1 (A/Michigan/45/2015) Hemagglutinin/HA1 HEK293 Cell Lysate (WB positive control)

MBS8116154-5x03mg 5x0.3mg
EUR 1205

Influenza A H1N1 (A/Melbourne/1/1946) Hemagglutinin/HA HEK293 Cell Lysate (WB positive control)

MBS8116187-03mg 0.3mg
EUR 280

Influenza A H1N1 (A/Melbourne/1/1946) Hemagglutinin/HA HEK293 Cell Lysate (WB positive control)

MBS8116187-5x03mg 5x0.3mg
EUR 1205

Influenza A H1N1 (A/Wisconsin/28/2011) Hemagglutinin/HA HEK293 Cell Lysate (WB positive control)

MBS8116205-03mg 0.3mg
EUR 280

Influenza A H1N1 (A/Wisconsin/28/2011) Hemagglutinin/HA HEK293 Cell Lysate (WB positive control)

MBS8116205-5x03mg 5x0.3mg
EUR 1205

Influenza A H1N1 (A/swine/Hebei/0116/2017) Hemagglutinin/HA Insect Cell Lysate (WB positive control)

MBS8119741-03mg 0.3mg
EUR 280

Influenza A H1N1 (A/swine/Hebei/0116/2017) Hemagglutinin/HA Insect Cell Lysate (WB positive control)

MBS8119741-5x03mg 5x0.3mg
EUR 1205

Influenza A H1N1 (A/Puerto Rico/8/1934) Hemagglutinin/HA Insect Cell Lysate (WB positive control)

MBS8114658-03mg 0.3mg
EUR 280

Influenza A H1N1 (A/Puerto Rico/8/1934) Hemagglutinin/HA Insect Cell Lysate (WB positive control)

MBS8114658-5x03mg 5x0.3mg
EUR 1205

Influenza A H1N1 (A/Puerto Rico/8/34) Hemagglutinin/HA HEK293 Cell Lysate (WB positive control)

MBS8114660-03mg 0.3mg
EUR 280

Influenza A H1N1 (A/Puerto Rico/8/34) Hemagglutinin/HA HEK293 Cell Lysate (WB positive control)

MBS8114660-5x03mg 5x0.3mg
EUR 1205

Influenza A H1N1 (A/swine/Ohio/23/1935) Hemagglutinin/HA HEK293 Cell Lysate (WB positive control)

MBS8116184-03mg 0.3mg
EUR 280

Influenza A H1N1 (A/swine/Ohio/23/1935) Hemagglutinin/HA HEK293 Cell Lysate (WB positive control)

MBS8116184-5x03mg 5x0.3mg
EUR 1205

Influenza A H1N1 (A/swine/Eire/89/1996) Hemagglutinin/HA HEK293 Cell Lysate (WB positive control)

MBS8116191-03mg 0.3mg
EUR 280

Influenza A H1N1 (A/swine/Eire/89/1996) Hemagglutinin/HA HEK293 Cell Lysate (WB positive control)

MBS8116191-5x03mg 5x0.3mg
EUR 1205

Influenza A H1N1 (A/Henry/1936) Neuraminidase/NA (His Tag) HEK293 Cell Lysate (WB positive control)

MBS8116248-03mg 0.3mg
EUR 280

Influenza A H1N1 (A/Henry/1936) Neuraminidase/NA (His Tag) HEK293 Cell Lysate (WB positive control)

MBS8116248-5x03mg 5x0.3mg
EUR 1205

Influenza A H5N8 HEK293 Cell Lysate (WB positive control)

MBS8116013-03mg 0.3mg
EUR 280

Influenza A H5N8 HEK293 Cell Lysate (WB positive control)

MBS8116013-5x03mg 5x0.3mg
EUR 1205

Influenza A H5N8 HEK293 Cell Lysate (WB positive control)

MBS8116019-03mg 0.3mg
EUR 280

Influenza A H5N8 HEK293 Cell Lysate (WB positive control)

MBS8116019-5x03mg 5x0.3mg
EUR 1205

Influenza A H1N1 (A/California/06/2009) Hemagglutinin/HA1 HEK293 Cell Lysate (WB positive control)

MBS8115991-03mg 0.3mg
EUR 280

Influenza A H1N1 (A/California/06/2009) Hemagglutinin/HA1 HEK293 Cell Lysate (WB positive control)

MBS8115991-5x03mg 5x0.3mg
EUR 1205

Influenza A H1N1 (A/swine/Cambridge/1939) Hemagglutinin/HA HEK293 Cell Lysate (WB positive control)

MBS8116185-03mg 0.3mg
EUR 280

Influenza A H1N1 (A/swine/Cambridge/1939) Hemagglutinin/HA HEK293 Cell Lysate (WB positive control)

MBS8116185-5x03mg 5x0.3mg
EUR 1205

Influenza A H1N1 (A/New Caledonia/20/99) Hemagglutinin/HA HEK293 Cell Lysate (WB positive control)

MBS8114657-03mg 0.3mg
EUR 280

Influenza A H1N1 (A/New Caledonia/20/99) Hemagglutinin/HA HEK293 Cell Lysate (WB positive control)

MBS8114657-5x03mg 5x0.3mg
EUR 1205

Influenza A H1N1 (A/Ohio/UR06-0091/2007) Hemagglutinin/HA HEK293 Cell Lysate (WB positive control)

MBS8114665-03mg 0.3mg
EUR 280

Influenza A H1N1 (A/Ohio/UR06-0091/2007) Hemagglutinin/HA HEK293 Cell Lysate (WB positive control)

MBS8114665-5x03mg 5x0.3mg
EUR 1205

Influenza A H1N1 (A/Ohio/07/2009) Hemagglutinin (HA1 Subunit) HEK293 Cell Lysate (WB positive control)

MBS8115760-03mg 0.3mg
EUR 280

Influenza A H1N1 (A/Ohio/07/2009) Hemagglutinin (HA1 Subunit) HEK293 Cell Lysate (WB positive control)

MBS8115760-5x03mg 5x0.3mg
EUR 1205

Influenza A H1N1 (A/USSR/90/197) Hemagglutinin (HA1 Subunit) HEK293 Cell Lysate (WB positive control)

MBS8115880-03mg 0.3mg
EUR 280

Influenza A H1N1 (A/USSR/90/197) Hemagglutinin (HA1 Subunit) HEK293 Cell Lysate (WB positive control)

MBS8115880-5x03mg 5x0.3mg
EUR 1205

Influenza A H1N1 (A/swine/Belgium/1/1998) Hemagglutinin/HA Insect Cell Lysate (WB positive control)

MBS8116026-03mg 0.3mg
EUR 280

Influenza A H1N1 (A/swine/Belgium/1/1998) Hemagglutinin/HA Insect Cell Lysate (WB positive control)

MBS8116026-5x03mg 5x0.3mg
EUR 1205

Influenza A H1N1 (A/Albany/12/1951) Hemagglutinin/HA Insect Cells Cell Lysate (WB positive control)

MBS8116067-03mg 0.3mg
EUR 280

Influenza A H1N1 (A/Albany/12/1951) Hemagglutinin/HA Insect Cells Cell Lysate (WB positive control)

MBS8116067-5x03mg 5x0.3mg
EUR 1205

Influenza A H1N1 (A/swine/Henan/SN13/2018) Hemagglutinin/HA HEK293 Cell Lysate (WB positive control)

MBS8116180-03mg 0.3mg
EUR 280

Influenza A H1N1 (A/swine/Henan/SN13/2018) Hemagglutinin/HA HEK293 Cell Lysate (WB positive control)

MBS8116180-5x03mg 5x0.3mg
EUR 1205

Influenza A H1N1 (A/swine/Saitama/21/2004) Hemagglutinin/HA HEK293 Cell Lysate (WB positive control)

MBS8116194-03mg 0.3mg
EUR 280

Influenza A H1N1 (A/swine/Saitama/21/2004) Hemagglutinin/HA HEK293 Cell Lysate (WB positive control)

MBS8116194-5x03mg 5x0.3mg
EUR 1205

Influenza A H1N1 (A/swine/Kansas/00246/2004) Hemagglutinin/HA HEK293 Cell Lysate (WB positive control)

MBS8116195-03mg 0.3mg
EUR 280


Disease coronavirus (COVID-19), which is caused by a coronavirus 2 acute respiratory syndrome (SARS-CoV-2), has been declared a pandemic. We here report the four COVID-19 cases with long-term positive viral ribonucleic acid (RNA) for about 61 days. Although treatment with human recombinant interferon, plasma recovered from COVID-19 patients, Arbidol, etc., the results of nucleic acid is still positive for SARS-CoV-2. After treatment with ritonavir danoprevir (DNVr, 100/100 mg, once daily), four patients showed 2-3 consecutive negative SARS-CoV-2 RNA and thus out of the hospital.

Kathleen

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