“Zooming in” on Glioblastoma: Understanding Tumor Heterogeneity and its Clinical Implications in the Era of Single-Cell Ribonucleic Acid Sequencing

“Zooming in” on Glioblastoma: Understanding Tumor Heterogeneity and its Clinical Implications in the Era of Single-Cell Ribonucleic Acid Sequencing

Glioblastoma (GBM) is the most common primary brain malignancy in adults and one of the most aggressive of all cancers in humans. It is very repetitive and treatment-resistant, largely because the infiltrative nature and inter- and intratumoral heterogeneity. This heterogeneity requires different landscape genomics and cell types within and between the tumor and the tumor microenvironment (TME). In the GBM, is the driving resistance heterogeneity of treatment, recurrence, and prognosis is poor, represent a major obstacle to personalized medicine.

Over the past decade, the sequencing technology has facilitated a deeper understanding of GBM heterogeneity by “zooming in” more progressive on tumor genomics and transcriptomics. initial efforts to use mass ribonucleic acid (RNA) sequencing, which examined the combined gene expression of tumor specimens as a whole. While innovative at the time, this bulk RNAseq mask important contribution of sub-populations of different tumor’s gene expression as a whole.

This work evolved into mass use RNA sequencing on tumor subsections anatomically and spatially distinct, previously unappreciated complexity exhibited genome of GBM. The revolutionary next step forward has been the emergence of a single cell RNA sequencing (scRNAseq), which examined the gene expression at the single cell level. scRNAseq has enabled us to understand in detail the heterogeneity GBM unprecedented.

We review studies of seminal in the development of our understanding of GBM heterogeneity, with a focus on scRNAseq and insight that have been provided in the understanding of GBM tumor mass, peritumoral space, and TME. We highlight the preclinical and clinical implications of this work and consider the potential impact of neuro-oncology, and to improve patient outcomes through personalized medicine.

"Zooming in" on Glioblastoma: Understanding Tumor Heterogeneity and its Clinical Implications in the Era of Single-Cell Ribonucleic Acid Sequencing
“Zooming in” on Glioblastoma: Understanding Tumor Heterogeneity and its Clinical Implications in the Era of Single-Cell Ribonucleic Acid Sequencing

[Knockdown of Fez family of zinc finger protein 1 antisense ribonucleic acid 1 (FEZF1-AS1) inhibits invasion and migration of esophageal squamous cell carcinoma cells by blocking the JAK2 / STAT3 pathway]

Objective To investigate the relationship between the long chain of non-coding RNA Fez family of zinc protein finger 1 antisense ribonucleic acid 1 (FEZF1-AS1) and invasion, migration and Janus kinase 2 / signal transducer and activator of transcription 3 (JAK2 / STAT3) signaling pathway in carcinoma squamous cell (ESCC) cells of the esophagus. Methods The expression ‘of FEZF1-AS1 in cancer tissues and cell lines ESCC ESCC was detected by real-time quantitative PCR.

After knocking out FEZF1-AS1 of KYSE150 and KYSE510 cells with expression vectors lentiviral built, changes in cell cycle were detected by flow cytometry, the ability of cell proliferation by colony test formations, the ability of cell invasion by TranswellTM invasion assay, the ability of cell migration by TranswellTM migration and early test, and the level of phosphorylated proteins JAK2 and STAT3 (p-STAT3) by Western blotting.

Recombinant Purified Hemagglutinin Influenza A Virus H1N1 H1 (H1N1) (A/New Caledonia/20/99) protein control for Western

H1N1-01-C 100 ul
EUR 343.2

NATtrol Influenza A/B Positive Control (6 X 0.5 mL)

NATFLUA/B-6MC 6 X 0.5 mL
EUR 227

NATtrol Influenza A/B  Positive Control (6 X 0.5 mL)

NATFLUAB-6C-IVD 6 X 0.5 mL
EUR 231

NATtrol Influenza A/B Positive Control (6 X 0.5 mL)

MDZ046 6 X 0.5 mL
EUR 272.16
Description: Please contact Gentaur in order to receive the datasheet of the product.

Influenza A virus HA Control/blocking peptide

AB-23091-P 100ug
EUR 196.8

NATtrol Influenza A H1N1 Positive Control (6 X 0.5 mL)

NATFLUAH1N1-6MC 6 X 0.5 mL
EUR 227

Influenza A H5N1 Hemagglutinin, (IN) Control Peptide

MBS659985-005mg 0.05mg
EUR 790

Influenza A H5N1 Hemagglutinin, (IN) Control Peptide

MBS659985-5x005mg 5x0.05mg
EUR 3395

NATtrol Influenza Negative Control (6 X 0.5 mL)

NATCXVA9-6MC 6 X 0.5 mL
EUR 220

Recombinant Purified Hemagglutinin Influenza A Virus (H11N2; A/duck/Yangzhou/906/2002) protein control for Western

H11N2-01-C 100 ul
EUR 343.2

Influenza B Virus IgA Control Serum

C1232A 3 mL
EUR 105

Influenza B Virus IgG Control Serum

C1232G 3 mL
EUR 105

Influenza B Virus IgM Control Serum

C1232M 3 mL
EUR 105

NATtrol Influenza/RSV Negative Control (6 x 0.5mL)

NATCXVA9-6C 6 x 0.5mL
EUR 220

NATtrol Influenza/RSV Positive Control (6 x 0.25mL)

NATFLURSV-6L 6 x 0.25mL
EUR 272

NATtrol Influenza A H1N1, External Run Control, Low (6 X 1 mL)

NATFLUAH1N1-ERCL 6 X 1 mL
EUR 360

NATtrol Influenza/RSV Negative Control (6 X 0.5 mL)

NATCXVA9-6C-IVD 6 X 0.5 mL
EUR 240

NATtrol Influenza/RSV Positive Control (6 x 0.5 mL)

NATFLURSV-6C 6 x 0.5 mL
EUR 221

NATtrol Influenza/RSV Negative Control (6 X 0.5 mL)

MDZ045 6 X 0.5 mL
EUR 272.16
Description: Please contact Gentaur in order to receive the datasheet of the product.

NATtrol Influenza A H1N1, External Run Control, Medium (6 X 1 mL)

NATFLUAH1N1-ERCM 6 X 1 mL
EUR 438

Influenza A H5N8 HEK293 Cell Lysate (WB positive control)

MBS8116013-03mg 0.3mg
EUR 280

Influenza A H5N8 HEK293 Cell Lysate (WB positive control)

MBS8116013-5x03mg 5x0.3mg
EUR 1205

Influenza A H5N8 HEK293 Cell Lysate (WB positive control)

MBS8116019-03mg 0.3mg
EUR 280

Influenza A H5N8 HEK293 Cell Lysate (WB positive control)

MBS8116019-5x03mg 5x0.3mg
EUR 1205

Influenza A, Avian, H5N1, Hemagglutinin (HA) (NT) Control Peptide

MBS633819-005mg 0.05mg
EUR 880

Influenza A, Avian, H5N1, Hemagglutinin (HA) (NT) Control Peptide

MBS633819-5x005mg 5x0.05mg
EUR 3820

Influenza A, Avian, H5N1, Neuraminidase (CT) (NA) Control Peptide

MBS655299-005mg 0.05mg
EUR 695

Influenza A, Avian, H5N1, Neuraminidase (CT) (NA) Control Peptide

MBS655299-5x005mg 5x0.05mg
EUR 2975

Influenza A, Avian, H5N1, Hemagglutinin (HA) (IN), Control Peptide

MBS658813-005mg 0.05mg
EUR 700

Influenza A, Avian, H5N1, Hemagglutinin (HA) (IN), Control Peptide

MBS658813-5x005mg 5x0.05mg
EUR 2990

Influenza Rapid Test Control Pack (3 X 1.5mL)

KZMC033 3 X 1.5mL
EUR 59

Influenza A H5N1, Nonstructural Protein 1 (NS1), Control Peptide

MBS658284-005mg 0.05mg
EUR 695

Influenza A H5N1, Nonstructural Protein 1 (NS1), Control Peptide

MBS658284-5x005mg 5x0.05mg
EUR 2975

NATtrol Influenza B, External Run Control, Low (6 X 1 mL)

NATFLUB-ERCL 6 X 1 mL
EUR 360

NATtrol Influenza B, External Run Control, Medium (6 X 1 mL)

NATFLUB-ERCM 6 X 1 mL
EUR 438

Influenza A virus (H5N1) matrix protein 2 Control/blocking peptide

M2E15-P 100 ug
EUR 196.8

Influenza A virus (H1N1) matrix protein 2 Control/blocking peptide

M2E16-P 100 ug
EUR 196.8

Influenza A virus (H9N2) matrix protein 2 Control/blocking peptide

M2E17-P 100 ug
EUR 196.8

Influenza A H5N1 (Avian) Nonstructural Protein 2 (NS2), Control Peptide

MBS633841-005mg 0.05mg
EUR 695

Influenza A H5N1 (Avian) Nonstructural Protein 2 (NS2), Control Peptide

MBS633841-5x005mg 5x0.05mg
EUR 2975

Influenza A, Avian, H5N1, Hemagglutinin (HA) (IN) Control Peptide (Bird Flu)

MBS659545-005mg 0.05mg
EUR 395

Influenza A, Avian, H5N1, Hemagglutinin (HA) (IN) Control Peptide (Bird Flu)

MBS659545-5x005mg 5x0.05mg
EUR 1630

Influenza A, Avian, IN H5N1, Neuraminidase (NA) Control Peptide (Bird Flu)

MBS655176-005mg 0.05mg
EUR 395

Influenza A, Avian, IN H5N1, Neuraminidase (NA) Control Peptide (Bird Flu)

MBS655176-5x005mg 5x0.05mg
EUR 1630

Influenza A, Avian, H5N1, CT, Neuraminidase (NA) Control Peptide (Bird Flu)

MBS655238-005mg 0.05mg
EUR 395

Influenza A, Avian, H5N1, CT, Neuraminidase (NA) Control Peptide (Bird Flu)

MBS655238-5x005mg 5x0.05mg
EUR 1630

Influenza A, Avian, H5N1, Hemagglutinin (HA) (NT) Control Peptide (Bird Flu)

MBS658994-005mg 0.05mg
EUR 395

Influenza A, Avian, H5N1, Hemagglutinin (HA) (NT) Control Peptide (Bird Flu)

MBS658994-5x005mg 5x0.05mg
EUR 1630

Influenza A H1N1 (A/Fort Monmouth/1/1947) Hemagglutinin/HA Insect Cell Lysate (WB positive control)

MBS8116115-03mg 0.3mg
EUR 280

Influenza A H1N1 (A/Fort Monmouth/1/1947) Hemagglutinin/HA Insect Cell Lysate (WB positive control)

MBS8116115-5x03mg 5x0.3mg
EUR 1205

Recombinant Purified Hemagglutinin Influenza A Virus H5N1 H5 (H5N1) (A/chicken/India/NIV33487/2006) (17-531aa) protein control for Western

H5N11-C 100 ul
EUR 343.2

Influenza A H1N1 (A/Fort Monmouth/1/1947) Hemagglutinin/HA1 HEK293 Cell Lysate (WB positive control)

MBS8116116-03mg 0.3mg
EUR 280

Influenza A H1N1 (A/Fort Monmouth/1/1947) Hemagglutinin/HA1 HEK293 Cell Lysate (WB positive control)

MBS8116116-5x03mg 5x0.3mg
EUR 1205

Influenza A H1N1 Nucleoprotein/NP Insect Cell Lysate (WB positive control)

MBS8114643-03mg 0.3mg
EUR 280

Influenza A H1N1 Nucleoprotein/NP Insect Cell Lysate (WB positive control)

MBS8114643-5x03mg 5x0.3mg
EUR 1205

Influenza A H2N2 Nucleoprotein/NP Insect Cell Lysate (WB positive control)

MBS8115797-03mg 0.3mg
EUR 280

Influenza A H2N2 Nucleoprotein/NP Insect Cell Lysate (WB positive control)

MBS8115797-5x03mg 5x0.3mg
EUR 1205

Influenza A H1N1 (A/WSN/1933) Hemagglutinin/HA Insect Cell Lysate (WB positive control)

MBS8114675-03mg 0.3mg
EUR 280

Influenza A H1N1 (A/WSN/1933) Hemagglutinin/HA Insect Cell Lysate (WB positive control)

MBS8114675-5x03mg 5x0.3mg
EUR 1205

Influenza A H1N1 (A/WSN/33) Hemagglutinin/HA HEK293 Cell Lysate (WB positive control)

MBS8114677-03mg 0.3mg
EUR 280

Influenza A H1N1 (A/WSN/33) Hemagglutinin/HA HEK293 Cell Lysate (WB positive control)

MBS8114677-5x03mg 5x0.3mg
EUR 1205

Influenza A H3N2 (A/X-31) Hemagglutinin/HA Insect Cell Lysate (WB positive control)

MBS8115815-03mg 0.3mg
EUR 280

Influenza A H3N2 (A/X-31) Hemagglutinin/HA Insect Cell Lysate (WB positive control)

MBS8115815-5x03mg 5x0.3mg
EUR 1205

Influenza A H3N2 (A/X-31) Hemagglutinin/HA HEK293 Cell Lysate (WB positive control)

MBS8115816-03mg 0.3mg
EUR 280

Influenza A H3N2 (A/X-31) Hemagglutinin/HA HEK293 Cell Lysate (WB positive control)

MBS8115816-5x03mg 5x0.3mg
EUR 1205

Influenza A H3N2 (A/Switzerland/9715293/2013) Nucleo Insect Cell Lysate (WB positive control)

MBS8116111-03mg 0.3mg
EUR 280

Influenza A H3N2 (A/Switzerland/9715293/2013) Nucleo Insect Cell Lysate (WB positive control)

MBS8116111-5x03mg 5x0.3mg
EUR 1205

Influenza A H1N1 (A/Bel/1942) Hemagglutinin/HA1 HEK293 Cell Lysate (WB positive control)

MBS8116114-03mg 0.3mg
EUR 280

Influenza A H1N1 (A/Bel/1942) Hemagglutinin/HA1 HEK293 Cell Lysate (WB positive control)

MBS8116114-5x03mg 5x0.3mg
EUR 1205

Influenza A H1N1 (A/WSN/1933) Hemagglutinin/HA HEK293 Cell Lysate (WB positive control)

MBS8116240-03mg 0.3mg
EUR 280

Influenza A H1N1 (A/WSN/1933) Hemagglutinin/HA HEK293 Cell Lysate (WB positive control)

MBS8116240-5x03mg 5x0.3mg
EUR 1205

Influenza A H1N1 (A/Denver/1957) Hemagglutinin/HA HEK293 Cell Lysate (WB positive control)

MBS8116188-03mg 0.3mg
EUR 280

Influenza A H1N1 (A/Denver/1957) Hemagglutinin/HA HEK293 Cell Lysate (WB positive control)

MBS8116188-5x03mg 5x0.3mg
EUR 1205

Influenza A H5N1 (A/China/2006) Hemagglutinin/HA HEK293 Cell Lysate (WB positive control)

MBS8116225-03mg 0.3mg
EUR 280

Influenza A H5N1 (A/China/2006) Hemagglutinin/HA HEK293 Cell Lysate (WB positive control)

MBS8116225-5x03mg 5x0.3mg
EUR 1205

Influenza A H1N1 (A/Ohio/07/2009) Hemagglutinin/HA HEK293 Cell Lysate (WB positive control)

MBS8115761-03mg 0.3mg
EUR 280

Influenza A H1N1 (A/Ohio/07/2009) Hemagglutinin/HA HEK293 Cell Lysate (WB positive control)

MBS8115761-5x03mg 5x0.3mg
EUR 1205

Influenza A H1N1 (A/USSR/90/77) Hemagglutinin/HA Insect Cell Lysate (WB positive control)

MBS8115879-03mg 0.3mg
EUR 280

Influenza A H1N1 (A/USSR/90/77) Hemagglutinin/HA Insect Cell Lysate (WB positive control)

MBS8115879-5x03mg 5x0.3mg
EUR 1205

Influenza A H1N1 (A/USSR/90/77) Neuraminidase/NA HEK293 Cell Lysate (WB positive control)

MBS8115960-03mg 0.3mg
EUR 280

Influenza A H1N1 (A/USSR/90/77) Neuraminidase/NA HEK293 Cell Lysate (WB positive control)

MBS8115960-5x03mg 5x0.3mg
EUR 1205

Influenza A H3N2 (A/Ohio/14/2008) Hemagglutinin/HA HEK293 Cell Lysate (WB positive control)

MBS8116234-03mg 0.3mg
EUR 280

Influenza A H3N2 (A/Ohio/14/2008) Hemagglutinin/HA HEK293 Cell Lysate (WB positive control)

MBS8116234-5x03mg 5x0.3mg
EUR 1205

Influenza A H1N1 (A/USSR/90/1977) Hemagglutinin/HA HEK293 Cell Lysate (WB positive control)

MBS8116241-03mg 0.3mg
EUR 280

Influenza A H1N1 (A/USSR/90/1977) Hemagglutinin/HA HEK293 Cell Lysate (WB positive control)

MBS8116241-5x03mg 5x0.3mg
EUR 1205

Influenza A virus (H5N1) matrix protein 2 hybrid sequence Control/blocking peptide

M2E11-P 100 ug
EUR 196.8

Influenza A H1N1 (A/Hawaii/70/2019) Nucleoprotein/NP Insect Cell Lysate (WB positive control)

MBS8119747-03mg 0.3mg
EUR 280

Influenza A H1N1 (A/Hawaii/70/2019) Nucleoprotein/NP Insect Cell Lysate (WB positive control)

MBS8119747-5x03mg 5x0.3mg
EUR 1205

Influenza A H3N2 (A/Kansas/14/2017) Neuraminidase/NA Insect Cell Lysate (WB positive control)

MBS8119886-INQUIRE INQUIRE Ask for price

Influenza A H5N1 (A/Anhui/1/2005) Hemagglutinin/HA HEK293 Cell Lysate (WB positive control)

MBS8114328-03mg 0.3mg
EUR 280

Influenza A H5N1 (A/Anhui/1/2005) Hemagglutinin/HA HEK293 Cell Lysate (WB positive control)

MBS8114328-5x03mg 5x0.3mg
EUR 1205

Influenza A H5N1 (A/Anhui/1/2005) Hemagglutinin/HA Insect Cell Lysate (WB positive control)

MBS8114329-03mg 0.3mg
EUR 280

Influenza A H5N1 (A/Anhui/1/2005) Hemagglutinin/HA Insect Cell Lysate (WB positive control)

MBS8114329-5x03mg 5x0.3mg
EUR 1205

Influenza A H5N1 (A/Anhui/1/2005) Hemagglutinin/HA HEK293 Cell Lysate (WB positive control)

MBS8114330-03mg 0.3mg
EUR 280

Influenza A H5N1 (A/Anhui/1/2005) Hemagglutinin/HA HEK293 Cell Lysate (WB positive control)

MBS8114330-5x03mg 5x0.3mg
EUR 1205

Influenza A H5N1 (A/Anhui/1/2005) Hemagglutinin/HA HEK293 Cell Lysate (WB positive control)

MBS8114332-03mg 0.3mg
EUR 280

Influenza A H5N1 (A/Anhui/1/2005) Hemagglutinin/HA HEK293 Cell Lysate (WB positive control)

MBS8114332-5x03mg 5x0.3mg
EUR 1205

Influenza A H2N2 (A/Japan/305/1957) Hemagglutinin/HA HEK293 Cell Lysate (WB positive control)

MBS8114417-03mg 0.3mg
EUR 280

Influenza A H2N2 (A/Japan/305/1957) Hemagglutinin/HA HEK293 Cell Lysate (WB positive control)

MBS8114417-5x03mg 5x0.3mg
EUR 1205

Influenza A H2N2 (A/Canada/720/2005) Hemagglutinin/HA Insect Cell Lysate (WB positive control)

MBS8114666-03mg 0.3mg
EUR 280

Influenza A H2N2 (A/Canada/720/2005) Hemagglutinin/HA Insect Cell Lysate (WB positive control)

MBS8114666-5x03mg 5x0.3mg
EUR 1205

Influenza A H2N2 (A/Canada/720/2005) Hemagglutinin/HA HEK293 Cell Lysate (WB positive control)

MBS8114668-03mg 0.3mg
EUR 280

Influenza A H2N2 (A/Canada/720/2005) Hemagglutinin/HA HEK293 Cell Lysate (WB positive control)

MBS8114668-5x03mg 5x0.3mg
EUR 1205

Influenza A H3N2 (A/Aichi/2/1968) Hemagglutinin/HA Insect Cell Lysate (WB positive control)

MBS8114705-03mg 0.3mg
EUR 280

Influenza A H3N2 (A/Aichi/2/1968) Hemagglutinin/HA Insect Cell Lysate (WB positive control)

MBS8114705-5x03mg 5x0.3mg
EUR 1205

Influenza A H3N2 (A/Aichi/2/1968) Hemagglutinin/HA HEK293 Cell Lysate (WB positive control)

MBS8114707-03mg 0.3mg
EUR 280

Influenza A H3N2 (A/Aichi/2/1968) Hemagglutinin/HA HEK293 Cell Lysate (WB positive control)

MBS8114707-5x03mg 5x0.3mg
EUR 1205

Influenza A H1N1 (A/Texas/05/2009) Hemagglutinin/HA HEK293 Cell Lysate (WB positive control)

MBS8115759-03mg 0.3mg
EUR 280

Influenza A H1N1 (A/Texas/05/2009) Hemagglutinin/HA HEK293 Cell Lysate (WB positive control)

MBS8115759-5x03mg 5x0.3mg
EUR 1205

Influenza A H5N1 (A/hubei/1/2010) Hemagglutinin/HA Insect Cell Lysate (WB positive control)

MBS8115770-03mg 0.3mg
EUR 280

Influenza A H5N1 (A/hubei/1/2010) Hemagglutinin/HA Insect Cell Lysate (WB positive control)

MBS8115770-5x03mg 5x0.3mg
EUR 1205

Influenza A H5N1 (A/Hubei/1/2010) Hemagglutinin/HA HEK293 Cell Lysate (WB positive control)

MBS8115771-03mg 0.3mg
EUR 280

Influenza A H5N1 (A/Hubei/1/2010) Hemagglutinin/HA HEK293 Cell Lysate (WB positive control)

MBS8115771-5x03mg 5x0.3mg
EUR 1205

Influenza A H3N2 (A/Babol/36/2005) Neuraminidase/NA HEK293 Cell Lysate (WB positive control)

MBS8115776-03mg 0.3mg
EUR 280

Influenza A H3N2 (A/Babol/36/2005) Neuraminidase/NA HEK293 Cell Lysate (WB positive control)

MBS8115776-5x03mg 5x0.3mg
EUR 1205

Influenza A H5N1 (A/Hubei/1/2010) Neuraminidase/NA HEK293 Cell Lysate (WB positive control)

MBS8115777-03mg 0.3mg
EUR 280

Influenza A H5N1 (A/Hubei/1/2010) Neuraminidase/NA HEK293 Cell Lysate (WB positive control)

MBS8115777-5x03mg 5x0.3mg
EUR 1205

Influenza A H3N2 (A/Perth/16/2009) Hemagglutinin/HA HEK293 Cell Lysate (WB positive control)

MBS8115807-03mg 0.3mg
EUR 280

Influenza A H3N2 (A/Perth/16/2009) Hemagglutinin/HA HEK293 Cell Lysate (WB positive control)

MBS8115807-5x03mg 5x0.3mg
EUR 1205

Influenza A H3N2 (A/Perth/16/2009) Hemagglutinin/HA0 Insect Cell Lysate (WB positive control)

MBS8115808-03mg 0.3mg
EUR 280

Influenza A H3N2 (A/Perth/16/2009) Hemagglutinin/HA0 Insect Cell Lysate (WB positive control)

MBS8115808-5x03mg 5x0.3mg
EUR 1205

Influenza A H5N1 (A/Hubei/1/2010) Hemagglutinin/HA1 HEK293 Cell Lysate (WB positive control)

MBS8115817-03mg 0.3mg
EUR 280

Influenza A H5N1 (A/Hubei/1/2010) Hemagglutinin/HA1 HEK293 Cell Lysate (WB positive control)

MBS8115817-5x03mg 5x0.3mg
EUR 1205

Influenza A H7N9 (A/Anhui/1/2013) Hemagglutinin/HA Insect Cell Lysate (WB positive control)

MBS8115839-03mg 0.3mg
EUR 280

Influenza A H7N9 (A/Anhui/1/2013) Hemagglutinin/HA Insect Cell Lysate (WB positive control)

MBS8115839-5x03mg 5x0.3mg
EUR 1205

Influenza A H7N9 (A/Anhui/1/2013) Hemagglutinin/HA HEK293 Cell Lysate (WB positive control)

MBS8115841-03mg 0.3mg
EUR 280

Influenza A H7N9 (A/Anhui/1/2013) Hemagglutinin/HA HEK293 Cell Lysate (WB positive control)

MBS8115841-5x03mg 5x0.3mg
EUR 1205

Influenza A H7N9 (A/Anhui/1/2013) Hemagglutinin/HA HEK293 Cell Lysate (WB positive control)

MBS8115842-03mg 0.3mg
EUR 280

Influenza A H7N9 (A/Anhui/1/2013) Hemagglutinin/HA HEK293 Cell Lysate (WB positive control)

MBS8115842-5x03mg 5x0.3mg
EUR 1205

Influenza A H7N9 (A/Anhui/1/2013) Neuraminidase/NA HEK293 Cell Lysate (WB positive control)

MBS8115855-03mg 0.3mg
EUR 280

Influenza A H7N9 (A/Anhui/1/2013) Neuraminidase/NA HEK293 Cell Lysate (WB positive control)

MBS8115855-5x03mg 5x0.3mg
EUR 1205

Influenza A H3N2 (A/Fujian/411/2002) Hemagglutinin/HA Insect Cell Lysate (WB positive control)

MBS8115867-03mg 0.3mg
EUR 280

Influenza A H3N2 (A/Fujian/411/2002) Hemagglutinin/HA Insect Cell Lysate (WB positive control)

MBS8115867-5x03mg 5x0.3mg
EUR 1205

Influenza A H1N1 (A/Taiwan/01/1986) Hemagglutinin/HA Insect Cell Lysate (WB positive control)

MBS8115874-03mg 0.3mg
EUR 280

Influenza A H1N1 (A/Taiwan/01/1986) Hemagglutinin/HA Insect Cell Lysate (WB positive control)

MBS8115874-5x03mg 5x0.3mg
EUR 1205

Influenza A H1N1 (A/Texas/36/1991) Hemagglutinin/HA Insect Cell Lysate (WB positive control)

MBS8115875-03mg 0.3mg
EUR 280

Influenza A H1N1 (A/Texas/36/1991) Hemagglutinin/HA Insect Cell Lysate (WB positive control)

MBS8115875-5x03mg 5x0.3mg
EUR 1205

Influenza A H3N2 (A/Sydney/5/1997) Hemagglutinin/HA Insect Cell Lysate (WB positive control)

MBS8115892-03mg 0.3mg
EUR 280

Influenza A H3N2 (A/Sydney/5/1997) Hemagglutinin/HA Insect Cell Lysate (WB positive control)

MBS8115892-5x03mg 5x0.3mg
EUR 1205

Influenza A H3N2 (A/Babol/36/2005) Hemagglutinin/HA Insect Cell Lysate (WB positive control)

MBS8115905-03mg 0.3mg
EUR 280

Influenza A H3N2 (A/Babol/36/2005) Hemagglutinin/HA Insect Cell Lysate (WB positive control)

MBS8115905-5x03mg 5x0.3mg
EUR 1205

Results FEZF1-AS1 are highly expressed in cancer tissues ESCC and FEZF1-AS1 expression in cells KYSE510 KYSE150 and higher than that in normal esophageal squamous epithelial cells. Upon knockdown FEZF1-AS1 expression, cell cycle and proliferation of cancer cells ESCC did not change obviously, but cell invasion and migration was significantly inhibited, and the protein levels decreased JAK2 and p-STAT3 protein increases. Conclusion FEZF1-AS1 knockdown blocks JAK2 / STAT3 pathway and inhibits cell invasion and migration of ESCC.

Kathleen

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